Drinking pattern and risk of non-fatal myocardial infarction: a population-based case-control study
Drinking pattern and risk of non-fatal myocardial infarction: a population-based case-control study
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DOI：
10.1111/j.1360-0443.2003.00630.x
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发表时间：
2004-03-01
期刊：
影响因子：
6
通讯作者：
Hovey, K
中科院分区：
文献类型：
--
作者：
Trevisan, M;Dorn, J;Hovey, K
AIMS饮酒与心脏病发病率和死亡率的降低有关。然而，大多数研究都集中在每一特定时间段的平均饮酒量上，而对饮酒模式关注较少。本研究旨在探讨不同饮酒方式与心肌梗死(MI)的关系。设计一项以人群为基础的病例对照研究。研究对象为427名发生MI的白人男性和905名健康白人男性对照(年龄35-69岁)。在计算机辅助访谈中，收集了访谈(对照组)或MI(病例)前12-24个月内饮酒模式的详细信息。与终生戒酒者相比，非当前饮酒者和当前饮酒者的调整后优势比(OR)和95%可信区间(CI)分别为0.66(0.3.1-1.39)和0.50(0.24-1.02)。与终生戒酒的人相比，每天饮酒的人的OR(0.41)明显更低。与主要用食物饮酒的参与者相比，主要不吃东西的参与者的OR为1.49(0.96-2.31)，与终生戒酒的参与者相比，OR为0.62(0.28-1.37)。报告只在周末饮酒的男性与每周饮酒少于一次的男性相比，MI的风险显著增加[1.91；(1.21-3.01)]，但与终生戒酒的男性相比[0.91(0.40-2.07)]。结论我们的结果表明饮酒模式对心血管健康有重要影响。
Aims Alcohol consumption has been associated with a reduced risk of heart disease incidence and mortality. However, most studies have focused on an average volume per specific time period and have paid little attention to the pattern of drinking. The aim of this study was to examine the association between various drinking patterns and myocardial infarction (MI).Design A population-based case-control study.Methods Participants were 427 white males with incident MI and 905 healthy white male controls (age 35-69 years) selected randomly from two Western New York counties. During computer-assisted interviews detailed information was collected regarding patterns of alcohol consumption during the 12-24 months prior to interview (controls) or MI (cases).Findings Compared to life-time abstainers, adjusted odds ratios (ORs) and 95% confidence interval (CI) for non-current and current drinkers were 0.66 (0.3.1-1.39) and 0.50 (0.24-1.02), respectively. Daily drinkers exhibited a Significantly lower OR (0.41) compared to life-time abstainers. Participants who drank mainly without food had an OR of 1.49 (0.96-2.31) compared to those who drank mainly with food and 0.62 (0.28-1.37) compared to life-time abstainers. Men who reported drinking only at weekends had a significantly greater MI risk [1.91; (1.21-3.01)] compared to men who drank less than once/week, but not compared to life-time abstainers [0.91 (0.40-2.07)].Conclusions Our results indicate that patterns of alcohol use have important cardiovascular health implications.