Caenorhabditis elegans expressing a Vitellogenin::GFP fusion protein show reduced embryo content and brood size.
Caenorhabditis elegans expressing a Vitellogenin::GFP fusion protein show reduced embryo content and brood size.
复制标题
DOI：
10.17912/micropub.biology.000532
复制
发表时间：
2022
影响因子：
--
通讯作者：
Hundley HA
中科院分区：
文献类型：
--
作者：
Erdmann EA;Abraham O;Hundley HA
卵黄原蛋白：绿色荧光蛋白融合蛋白已被用于秀丽隐杆线虫卵黄的合成、内吞作用和功能的研究。在这里，我们报告了一种常用的含有vit2::gfp融合的转基因菌株在繁殖中显示缺陷，导致成虫的胚胎含量和卵量显着降低。
Vitellogenin::GFP fusion proteins have been used in several studies of the synthesis, endocytosis, and function of yolk in Caenorhabditis elegans. Here we report that one commonly used transgenic strain harboring a vit-2::gfp fusion displays defects in reproduction that lead to a significantly decreased embryo content and brood size in adult worms.