Hydrolysis of functional monomers in a single-bottle self-etching primer -: Correlation of 13C NMR and TEM findings
Hydrolysis of functional monomers in a single-bottle self-etching primer -: Correlation of 13C NMR and TEM findings
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DOI：
10.1177/154405910608500505
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发表时间：
2006-05-01
影响因子：
7.6
通讯作者：
King, NM
中科院分区：
文献类型：
--
作者：
Nishiyama, N;Tay, FR;King, NM
将联合收割机酸性甲基丙烯酸酯单体与水结合在单个瓶中的自蚀刻底漆/粘合剂水解不稳定，需要冷藏以延长其保质期。本研究检验了零假设，即含4-MET的简化自蚀刻底漆的一年间歇性冷藏不会导致可通过透射电子显微镜和C-13 NMR光谱识别的水解变化。人类牙本质在打开包装后立即与UniFil Bond粘合，或在4 ℃下间歇冷藏一年后粘合。通过NMR分析新鲜和老化引物的化学变化。超微结构的观察表明，有一个增强蚀刻能力的老化粘合剂，不伴随着树脂渗透或有效的聚合。从老化的乙醇基底漆中检测到的新NMR峰证实，降解最初是通过与乙醇的酯化反应发生的，然后是4-MET中两个酯基的水解。尽管间歇制冷，功能性甲基丙烯酸酯单体仍会发生水解。
Self-etching primers/adhesives that combine acidic methacrylate monomers with water in a single bottle are hydrolytically unstable and require refrigeration to extend their shelf-lives. This study tested the null hypothesis that one year of intermittent refrigeration of a 4-MET-containing simplified self-etching primer does not result in hydrolytic changes that are identifiable by transmission electron microscopy and C-13 NMR spectroscopy. Human dentin was bonded with UniFil Bond immediately after being unpacked, or after one year of intermittent refrigeration at 4 degrees C. Fresh and aged primers were analyzed by NMR for chemical changes. Ultrastructural observations indicated that there was an augmentation in etching capacity of the aged adhesive that was not accompanied by resin infiltration or effective polymerization. New NMR peaks detected from the aged ethanol-based primer confirmed that degradation occurred initially via esterification with ethanol, followed by hydrolysis of both ester groups in the 4-MET. Hydrolysis of functional methacrylate monomers occurs despite intermittent refrigeration.