A Smartphone App Reveals Erratic Diurnal Eating Patterns in Humans that Can Be Modulated for Health Benefits.
A Smartphone App Reveals Erratic Diurnal Eating Patterns in Humans that Can Be Modulated for Health Benefits.
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DOI：
10.1016/j.cmet.2015.09.005
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发表时间：
2015-11-03
期刊：
影响因子：
29
通讯作者：
Panda S
中科院分区：
文献类型：
--
作者：
Gill S;Panda S
禁食的昼夜节律促进健康，但人类的饮食模式很少被评估。使用移动的应用程序，我们监测了几天没有轮班工作的健康成年人的摄入事件。大多数受试者在清醒时间和夜间禁食期间经常和不规律地进食。有一种倾向于晚吃饭，估计<25% calories being consumed before noon and >有35%的人在下午6点后吃饭。由于平日/周末饮食模式的变化，类似于跨时区旅行，因此“代谢时差”很普遍。半数队列的每日摄入持续时间（95%间隔）超过14.75小时。当进食持续时间>14小时的超重个体在我们开发的数据可视化（饮食摄入模式的光栅图，“feedogram”）的帮助下，每天只吃10-11小时，持续16周时，他们减轻了体重，报告说精力充沛，改善了睡眠。效益持续了一年。
A diurnal rhythm of eating-fasting promotes health, but humans’ eating pattern is rarely assessed. Using a mobile app, we monitored ingestion events in healthy adults with no shift-work for several days. Most subjects ate frequently and erratically throughout wakeful hours and overnight fasting duration paralleled time in bed. There was a bias toward eating late, with estimated <25% calories being consumed before noon and >35% after 6pm. “Metabolic jetlag” resulting from weekday/weekend variation in eating pattern akin to travel across time-zones was prevalent. The daily intake duration (95% interval) exceeded 14.75 h for half the cohort. When overweight individuals with >14 h eating duration ate for only 10–11 h daily for 16 weeks assisted by a data visualization (raster plot of dietary intake pattern, “feedogram”) that we developed, they reduced body weight, reported being energetic, and improved sleep. Benefits persisted for a year.