(4+1)-Cycloadditions Exploiting the Biphilicity of Oxyphosphonium Enolates and RhII/PdII-Stabilized Metallocarbenes for the Construction of Five-Membered Frameworks
(4+1)-Cycloadditions Exploiting the Biphilicity of Oxyphosphonium Enolates and RhII/PdII-Stabilized Metallocarbenes for the Construction of Five-Membered Frameworks
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DOI：
10.1055/s-0040-1706009
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发表时间：
2021-01
期刊：
影响因子：
2
通讯作者：
Zachary D. Tucker;B. Ashfeld
中科院分区：
文献类型：
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作者：
Zachary D. Tucker;B. Ashfeld
摘要（4+1）环化反应是一种未充分利用的五元杂环和碳环框架的形成断开。在这里，我们分析的方法，采用oxyphosphonium烯醇化物和RhII/PdII-C1-C 1引言2（4+1）-使用Kukhtin-Ramirez-Like反应性的环化3（4+1）-使用环丙烷化/扩环序列的环化4 Pd-催化的（4+1）-通过卡宾迁移插入/还原消除过程的环化5总结
Abstract (4+1)-Cyclizations are an underutilized disconnect for the formation of five-membered heterocyclic and carbocyclic frameworks. Herein we analyze methods employing oxyphosphonium enolates and RhII/PdII-metallocarbenes as C1 synthons in the presence of several four-atom components for the synthesis of 2,3-dihydrobenzofurans, 2,3-dihydroindoles, oxazolones, cyclopentenones, and pyrrolones. 1 Introduction 2 (4+1)-Cyclizations Employing Kukhtin–Ramirez-Like Reactivity 3 (4+1)-Cyclizations Employing a Cyclopropanation/Ring-Expansion Sequence 4 Pd-Catalyzed (4+1)-Cyclizations through Carbene Migratory Insertion/Reductive Elimination Processes 5 Summary