Task dependence of responses in first dorsal interosseous muscle to magnetic brain stimulation in man.
Task dependence of responses in first dorsal interosseous muscle to magnetic brain stimulation in man.
复制标题
人类第一背侧骨间肌对磁脑刺激反应的任务依赖性。
DOI：
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
R. Lemon
中科院分区：
文献类型：
--
作者：
D. Flament;P. Goldsmith;C. J. Buckley;R. Lemon
1. 在进行不同的手工任务时，研究了第一背骨间肌（1DI）对大脑非侵入性磁刺激和头皮电刺激的反应。2. 测试的六项任务需要激活1DI肌，要么是单独的（在食指外展时），要么是作为更复杂的肌肉协同模式的一部分（例如在握力时）。通过向受试者提供他们的肌肉活动的视觉反馈，在不同的任务中保持1DI肌电活动水平不变。3. 在每个受试者（n = 14）中，磁刺激在执行复杂任务时产生的反应比在执行简单的指数溯因任务时产生的反应更大。所有受试者的汇总结果显示，5个复杂任务中有4个与显著较大的1DI反应相关（配对t检验，P < 0.05）。4. 这些结果在单个运动单元水平上得到了证实，记录了来自6个受试者的9个运动单元。受试者被要求在执行不同的任务时稳定地释放同一运动单元。在复杂的任务（旋转或钳握）中，响应磁刺激的运动单元放电的概率明显大于外展。5. 对三名受试者进行了头皮电刺激，阴极在顶点，阳极在对侧运动皮层。不同任务下的反应振幅模式与磁刺激下的相似，但任务相关差异较小。6. 这些结果表明，在不同的任务执行过程中，磁刺激引起的皮质脊髓齐射可能在振幅上有所不同。我们还讨论了可能导致这种变异的与任务相关的皮层机制。
1. The response of the first dorsal interosseous (1DI) muscle to non‐invasive magnetic and scalp electrical stimulation of the brain have been investigated during performance of different manual tasks. 2. The six tasks tested required activation of the 1DI muscle, either in isolation (during abduction of the index finger) or as part of a more complex pattern of muscle synergies (e.g. during power grip). The level of 1DI EMG activity across tasks was kept constant by providing subjects with visual feedback of their muscle activity. 3. In every subject (n = 14) magnetic stimulation produced larger responses during performance of complex tasks than during the simple index abduction task. The pooled results from all subjects showed that four of the five complex tasks were associated with significantly larger 1DI responses (paired t test, P < 0.05). 4. These results were confirmed at the single motor unit level for nine motor units recorded from six subjects. Subjects were requested to produce a steady discharge of the same motor unit during performance of different tasks. The probability of motor unit discharge in response to magnetic stimulation was significantly greater during complex tasks (rotation or pincer grips) than during abduction. 5. Scalp electrical stimulation was performed in three subjects with the cathode at the vertex and the anode over the contralateral motor cortex. The pattern of response amplitudes in the different tasks tended to parallel that obtained for magnetic stimulation, but the task‐related differences were smaller. 6. These results suggest that during performance of the different tasks, the corticospinal volleys evoked by magnetic stimulation may vary in amplitude. The task‐related cortical mechanisms that may contribute to this variability are discussed.
皮质脊髓和红核脊髓控制肢体运动的神经机制。
影响因子：
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作者：
Cheney,PD;Fetz,EE;Mewes,K
通讯作者：
Mewes,K
影响因子：
2.5
作者：
FETZ, EE;CHENEY, PD
通讯作者：
CHENEY, PD
灵长类运动皮层细胞和肌肉之间的功能关系：固定和灵活。
DOI：
10.1002/9780470513545.ch7
发表时间：
1987
期刊：
Ciba Foundation symposium
影响因子：
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作者：
Fetz,EE;Cheney,PD
通讯作者：
Cheney,PD