ECTOPIC PROSTATIC TISSUE IN URETHRA - CLINICOPATHOLOGICAL ENTITY AND A SIGNIFICANT CAUSE OF HEMATURIA

ECTOPIC PROSTATIC TISSUE IN URETHRA - CLINICOPATHOLOGICAL ENTITY AND A SIGNIFICANT CAUSE OF HEMATURIA
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DOI:
10.1016/s0022-5347(17)61468-x
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发表时间:
1971-01-01
期刊:
影响因子:
6.6
通讯作者:
ABELL, MR
ABELL, MR
中科院分区:
医学1区
文献类型:
--
作者:
BUTTERICK, JD;SCHNITZER, B;ABELL, MR

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材料与方法对1960年7月至1969年7月间发现的73例尿道异位前列腺组织,其中5例因组织诊断可疑、活检部位不确定及临床资料严重不足而被排除。一例膀胱异位组织也被排除在外。2对其余完全可接受病例的临床表现和膀胱镜及显微镜特征进行详细评估。其中5例可能包括在Nesbit的报告中。1除了对所有标本进行常规苏木精和伊红染色外,还对一些病例的切片进行了钙、铁和酸性磷酸酶的染色,染色方法为Gomori技术、周期性酸-希夫反应和阿利新绿。取3例患者的尿道异位前列腺组织和1例良性腺体增生患者的前列腺组织进行超微结构研究。这些组织立即浸入冷的含钙酸盐缓冲的4%戊二醛(pH值7.4)中,切成1毫米的立方体,固定24小时。组织块后固定在Zetterqvist的3锇溶液中,
MATERIALS AND METHODSOf 73 cases of ectopic prostatic tissue of the urethra seen between July 1960 and July 1969, 5 cases were excluded from detailed consideration because of questionable tissue diagnoses, uncertainty as to site of biopsy and grossly inadequate clinical information. One example of ectopic tissue in the bladder was also excluded. 2 Clinical findings and the cystoscopic and microscopic characteristics of the remaining fully acceptable cases were assessed in detail. Five of these cases were probably included in the report by Nesbit. 1 In addition to routine hematoxylin and eosin stained preparations on all specimens, sections from a number of cases were stained for calcium, iron and acid phosphatase by the Gomori technique, by the periodic acid-Schiff reaction and with alcian green.Ectopic prostatic tissue from the urethra of 3 patients and prostatic tissue from 1 patient with benign glandular hyperplasia were prepared for ultrastructural studies. These tissues were immersed immediately in cold cacodylate-buffered 4 per cent glutaraldehyde, pH 7.4, diced into 1 mm. cubes and fixed for 24 hours. Tissue blocks were post-fixed in Zetterqvist's3 osmium solution,