Cystic Fibrosis Pulmonary Guidelines Treatment of Pulmonary Exacerbations
Cystic Fibrosis Pulmonary Guidelines Treatment of Pulmonary Exacerbations
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DOI：
10.1164/rccm.200812-1845pp
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发表时间：
2009-11-01
影响因子：
24.7
通讯作者：
Marshall, Bruce C.
中科院分区：
文献类型：
--
作者：
Flume, Patrick A.;Mogayzel, Peter J., Jr.;Marshall, Bruce C.
囊性纤维化肺病的自然病程是一个慢性进展过程，伴有间歇性的急性症状恶化，通常称为急性肺加重，这些加重通常需要医疗干预。重要的是，在现有有效性和安全性证据的基础上推荐适当的治疗方法。因此，囊性纤维化基金会成立了一个委员会，以确定与肺恶化相关的关键问题，使用循证方法审查临床证据，并向临床医生提供建议。希望这些指南能对临床医生治疗囊性纤维化患者有所帮助。
The natural history of cystic fibrosis lung disease is one of chronic progression with intermittent episodes of acute worsening of symptoms frequently called acute pulmonary exacerbations These exacerbations typically warrant medical intervention. It is important that appropriate therapies are recommended on the basis of available evidence of efficacy and safety. The Cystic Fibrosis Foundation therefore established a committee to define the key questions related to pulmonary exacerbations, review the clinical evidence using an evidence-based methodology, and provide recommendations to clinicians. It is hoped that these guidelines will be helpful to clinicians in the treatment of individuals with cystic fibrosis.