Retinal microangiopathy in systemic lupus erythematosus.
Retinal microangiopathy in systemic lupus erythematosus.
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系统性红斑狼疮的视网膜微血管病变。
DOI：
10.1016/0002-9394(75)90140-3
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发表时间：
1975
影响因子：
4.2
通讯作者：
G. Ibáñez
中科院分区：
文献类型：
--
作者：
R. Santos;E. Barojas;D. Alarcon;G. Ibáñez
我们对50例中度活动期或非活动期系统性红斑狼疮患者进行了完整的眼部检查，包括眼底荧光素血管造影;无眼部症状。1例患者有玻璃疣，2例患者有眼内压升高，盘杯归因于口服皮质类固醇。没有患者通过检眼镜检查发现异常。尽管这种表面上正常的条件下，荧光素血管造影显示单一或多个微动脉瘤9例（13只眼）和视网膜毛细血管扩张与荧光素渗漏6例（6只眼）。两例患者均发生异常。中度红斑狼疮患者的毛细血管改变可能是以前急性血管炎的残留，可能是由于免疫复合物沉积。
We performed complete ocular examination, including fluorescein angiography of the fundus, in 50 ambulatory patients with moderately active or inactive systemic lupus erythematosus; none had ocular symptoms. One patient had drusen and two patients had increased intraocular pressures with disk cupping attributable to orally administered corticosteroids. No patient had detectable abnormalities by ophthalmoscopic examination. Despite this apparently normal condition, fluorescein angiography revealed single or multiple microaneurysms in nine patients (13 eyes) and retinal capillary dilatations with leakage of fluorescein in six patients (six eyes). Both abnormalities occurred in two patients. These capillary changes in moderately ill patients with lupus erythematosus are probably the residue of previous acute vasculitis, perhaps due to immune-complex deposition.