Birth size and accelerated growth during infancy are associated with increased odds of childhood overweight in Mexican children
Birth size and accelerated growth during infancy are associated with increased odds of childhood overweight in Mexican children
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DOI：
10.1016/j.jada.2007.09.011
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发表时间：
2007-12-01
影响因子：
--
通讯作者：
Neufeld, Lynnette M.
中科院分区：
文献类型：
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作者：
Jones-Smith, Jessica C.;Fernald, Lia C. H.;Neufeld, Lynnette M.
目的 在低收入和中等收入国家的当代人群中，出生体型、婴儿期生长速度和儿童超重几率之间的关系尚未得到彻底调查。本研究的主要目的是评估出生体重（使用出生时体重指数）和婴儿期加速生长（定义为出生至 1 岁之间的向上生长曲线百分位数交叉）对儿童超重几率的影响。第二个目标是描述婴儿期加速生长的社会人口统计学相关性。设计观察性前瞻性队列。受试者/环境参与者是居住在墨西哥城郊的 163 名儿童及其母亲，最初在 1997 年至 2000 年期间招募，一直跟踪到 2005 年。主要结果指标主要结果是儿童超重（根据体重指数评估）。次要结果是婴儿期加速生长。进行的统计分析使用多元线性回归和逻辑回归来确定出生体型、加速生长和儿童超重之间的关联。结果出生时体型增大和生命第一年加速生长增加了儿童超重的几率（比值比 [OR] 7.62，P
Objective The associations of birth size, rate of growth during infancy, and odds of childhood overweight have not yet been thoroughly investigated in contemporary cohorts in low- and middle-income countries. The primary aim of this study was to evaluate the influence of birth size (using body mass index at birth) and accelerated growth during infancy (defined as upward growth curve percentile crossing between birth and age 1 year) on the odds of childhood overweight. A secondary goal was to characterize the sociodemographic correlates of accelerated growth during infancy.Design Observational prospective cohort.Subjects/setting Participants were 163 children and their mothers living in semiurban Mexico who were originally recruited between 1997 and 2000 and followed until 2005.Main outcome measures Primary outcome was childhood overweight (as assessed by body mass index). Secondary outcome was accelerated growth during infancy.Statistical analyses performed Multivariate linear regression and logistic regression were used to determine the associations among birth size, accelerated growth, and childhood overweight.Results Increased size at birth and accelerated growth during the first year of life increased the odds of childhood overweight (odds ratio [OR] 7.62, P