Biologically inspired microtexturing: investigation into the surface topography of next-generation neurosurgical probes.
Biologically inspired microtexturing: investigation into the surface topography of next-generation neurosurgical probes.
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受生物学启发的微纹理：对下一代神经外科探针的表面形貌的研究。
DOI：
10.1109/iembs.2008.4650486
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发表时间：
2008
期刊：
影响因子：
--
通讯作者：
Frasson L
中科院分区：
文献类型：
--
作者：
Frasson L
微创(MI)手术代表了许多类型医疗干预的未来(锁孔神经外科、自然开口经内窥镜手术等)。然而，当今手术工具的缺点助长了开发下一代“智能器械”的需要，这种器械对患者来说将更准确、更安全。本文介绍了一种基于UV光刻的生物启发的微纹理方法的初步结果，以及它在MI神经外科中的应用。这些结果表明，神经外科探头外表面“打印”的纹理的大小和几何形状显然会影响在大脑-探头界面产生的插入和提取力。因此，通过仔细选择适当的微结构，可以获得独特的插入特性，这可以改善现有仪器的性能(例如，减少永久电极的滑移，例如用于脑深部刺激的电极)或完全能够开发新的设计。
Minimally Invasive (MI) surgery represents the future of many types of medical intervention (keyhole neurosurgery, natural orifice trans-luminal endoscopic surgery, etc.). However, the shortcomings of today's surgical tools fuel the need for the development of next-generation “smart instrumentation”, which will be more accurate and safer for the patient. This paper presents the preliminary results of a biologically inspired microtexturing method, based on UV-lithography, and its application to MI neurosurgery. These results suggest that the size and geometry of the texture “printed” on the outer surface of a neurosurgical probe clearly affect the insertion and extraction forces generated at the brain-probe interface. Thus, by carefully choosing an appropriate microtexture, unique insertion characteristics can be obtained, which can improve the performance of existing instruments (e.g. reducing slippage in permanent electrodes such as those used in deep brain stimulation) or enable the development of novel designs altogether.