Throbbing pain is related to Queckenstedt's test effect in migraine patients
Throbbing pain is related to Queckenstedt's test effect in migraine patients
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DOI：
10.1111/j.1468-2982.2008.01746.x
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发表时间：
2009-03-01
期刊：
影响因子：
4.9
通讯作者：
Wang, S-J
中科院分区：
文献类型：
--
作者：
Chou, C-H;Fuh, J-L;Wang, S-J
Queckenstedt（Q）试验可加重偏头痛发作期间的头痛强度（Q试验效应）。本研究的目的是描述Q测试对偏头痛发作患者的影响。我们对39名急性偏头痛发作的患者在仰卧位和坐姿下进行了30秒的Q测试和假测试。头痛强度期间和30秒后，Q-或假测试记录在0-10口头规模。在患者的面部和前臂上使用纱布刷牙测试后记录刷牙异常性疼痛（BA）。在坐姿和仰卧位，Q-而不是假测试加重了头痛强度。搏动性疼痛和更高的疼痛强度的存在与仰卧位的Q测试效应相关。然而，BA的存在或不存在并不相关。我们的结论是，Q-试验效应可能与脑膜的外周致敏有关，但与中枢致敏无关。Q试验效应可作为外周致敏的客观指标。
The Queckenstedt's (Q)-test can aggravate headache intensity during migraine attacks (Q-test effect). The objective of this study was to delineate the Q-test effect in patients experiencing migraine attacks. We performed a 30-s Q- and a sham test on 39 patients with acute migraine attacks in both supine and sitting positions. Headache intensities during and 30 s after the Q- or sham tests were recorded on a 0-10 verbal scale. Brushing allodynia (BA) was recorded after using a gauze-brushing test over the patient's face and forearms. The Q- but not the sham test aggravated headache intensity in both sitting and supine positions. The presence of throbbing pain and higher pain intensities was associated with the Q-test effect in the supine position. However, the presence or absence of BA was not correlated. We concluded that the Q-test effect is likely to be related to peripheral sensitization of the meninges but not central sensitization. The Q-test effect may be used as an objective marker for peripheral sensitization.