EHRLICHIOSIS - A CAUSE OF PROLONGED FEVER
EHRLICHIOSIS - A CAUSE OF PROLONGED FEVER
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DOI：
10.1093/clinids/20.4.821
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发表时间：
1995-04-01
影响因子：
11.8
通讯作者：
EVERETT, ED
中科院分区：
文献类型：
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作者：
ROLAND, WE;MCDONALD, G;EVERETT, ED
人类埃立克体病是一种最近描述的疾病，被认为是蜱传的。人类埃立克体病的大多数公认病例表现为急性非特异性发热性疾病，未经治疗的症状性疾病的自然史在很大程度上是未知的。在4年的时间里，我们通过血清学检测、聚合酶链反应分析或两种方法同时进行，确定了41例人类埃立克体病。其中6名患者的主要发现是持续发热。发热持续时间为17 ~ 51天。在就诊时，所有6例患者的临床特征、实验室特征或两者均符合埃立克体病的诊断。聚合酶链反应分析有助于快速确认五名患者中四名的诊断。对于居住在流行区的长期发热患者，应考虑诊断为埃立克体病。
Human ehrlichiosis is a recently described illness that is thought to be tick-borne. Most recognized cases of human ehrlichiosis manifest as an acute nonspecific febrile illness, The natural history of untreated symptomatic disease is largely unknown. Over a 4-year period, we identified 41 cases of human ehrlichiosis by serological testing, polymerase chain reaction analysis, or both methods. The principal finding for six of the patients was protracted fever. The duration of their fevers ranged from 17 to 51 days. At the time of presentation, all six patients had clinical features, laboratory features, or both consistent with a diagnosis of ehrlichiosis. Polymerase chain reaction analysis helped to rapidly confirm the diagnosis for four of five patients tested. The diagnosis of human ehrlichiosis should be considered for patients with prolonged fever who live in an area of endemicity.