Mechanisms and streams for processing of "what" and "where" in auditory cortex
Mechanisms and streams for processing of "what" and "where" in auditory cortex
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DOI：
10.1073/pnas.97.22.11800
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发表时间：
2000-10-24
影响因子：
11.1
通讯作者：
Tian, B
中科院分区：
文献类型：
--
作者：
Rauschecker, JP;Tian, B
用不同类型的复杂声音研究了恒河猴听皮层多个区域的功能专门化和层次化组织。将颞上回外侧带区域的神经元调谐到带通噪声爆发的最佳中心频率和带宽。他们对线性调频扫描的速度和方向也是有选择性的。许多神经元表现出对有限数量的特定物种的发声(“猴子叫声”)的偏好。这些响应选择性可以用非线性光谱和时间积分机制来解释。在一系列单独的实验中，猴子的叫声被呈现在不同的空间位置，并确定了侧带神经元对猴子叫声和空间位置的调谐。在三个带区域中，前外侧区域对猴子叫声的特异性最高，而尾侧区域的神经元显示出最大的空间选择性。我们的结论是，灵长类的皮质听觉系统至少分为两个处理流，一个是起源于颞上回尾部并投射到顶叶皮质的空间流，另一个是起源于侧带更前部的模式或客体流。通过使用功能神经成像，可以在人类听觉皮质中看到类似的分工。
The functional specialization and hierarchical organization of multiple: areas in rhesus monkey auditory cortex were examined with various types of complex sounds. Neurons in the lateral belt areas of the superior temporal gyrus were tuned to the best center frequency and bandwidth of band-passed noise bursts. They were also selective for the rate and direction of linear frequency modulated sweeps. Many neurons showed a preference for a limited number of species-specific vocalizations ("monkey calls"). These response selectivities can be explained by nonlinear spectral and temporal integration mechanisms. In a separate series of experiments, monkey calls were presented at different spatial locations, and the tuning of lateral belt neurons to monkey calls and spatial location was determined. Of the three belt areas the anterolateral area shows the highest degree of specificity for monkey calls, whereas neurons in the caudolateral area display the greatest spatial selectivity. We conclude that the cortical auditory system of primates is divided into at least two processing streams, a spatial stream that originates in the caudal part of the superior temporal gyrus and projects to the parietal cortex, and a pattern or object stream originating in the more anterior portions of the lateral belt. A similar division of labor can be seen in human auditory cortex by using functional neuroimaging.