Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Stem Bark of Ceiba pentandra Gaertn

Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Stem Bark of Ceiba pentandra Gaertn
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木棉茎皮水提物的抗炎镇痛作用

DOI:
10.4236/pp.2014.512121
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发表时间:
2014
期刊:
Pharmacology & Pharmacy
影响因子:
--
通讯作者:
A. Abena
A. Abena
中科院分区:
--
文献类型:
--
作者:
R. E. Itou;R. Sanogo;A. W. E. Ossibi;Freddy Gelase Nsondé Ntandou;R. Ondélé;B. Peneme;Nadége Okiémy Andissa;D. Diallo;J. Ouamba;A. Abena

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用大鼠和小鼠实验记录了五角草茎皮水提物的抗炎、镇痛作用。角叉菜胶和棉球诱导炎症反应。采用镇痛仪、Koster法和热板法对大鼠进行疼痛研究。五角草水提物(400和800 mg/kg)具有显著的抗炎、镇痛作用。Flavono吗?提取物中存在的Ds似乎是造成这种活性的原因。
Anti-inflammatory and analgesic effects of the aqueous extract of the stem bark of Ceiba pentandra Gaertn (Bombacaceae) were recorded in rat and mice. Inflammation was induced by carrageenan and cotton pellet. The pain was studied using analgesymeter, Koster and hot plate Methods. Aqueous extract (400 and 800 mg/kg) of Ceiba pentandra presents a significant anti-inflammatory and analgesic activity. Flavono?ds present in the extract seem to be responsible for the activity.