Electromagnetic therapeutic angiogenesis: The next step

Electromagnetic therapeutic angiogenesis: The next step
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DOI:
10.1080/01616412.2000.11740682
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发表时间:
2000-06-01
影响因子:
1.9
通讯作者:
Asin-Cardiel, E
Asin-Cardiel, E
中科院分区:
医学4区
文献类型:
--
作者:
Cuevas, P;Asin-Cardiel, E

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以生长因子蛋白施用或基因治疗的形式的治疗性血管生成是治疗患有严重冠状动脉和外周动脉疾病的患者的新方法,所述严重冠状动脉和外周动脉疾病不适于常规的血管重建方法。此外,一种新的实验策略通过电磁刺激增加缺血组织中的内源性血管生成以诱导局部“血管生成素”。进一步的研究检查电磁血管生成的分子基础和临床疗效是必要的。
Therapeutic angiogenesis, in the form of growth factor protein administration or gene therapy, is a new method of treatment for patients with severe coronary and peripheral artery disease not amenable to conventional methods of revascularization. Furthermore, a new experimental strategy increases endogenous angiogenesis in ischemic tissue to induce local 'angiogens' by means of electromagnetic stimulation. Further studies examining the molecular basis and clinical efficacy of electromagnetic angiogenesis are necessary.