Pessimistic, anxious, and depressive personality traits predict all-cause mortality: the Mayo Clinic cohort study of personality and aging.
Pessimistic, anxious, and depressive personality traits predict all-cause mortality: the Mayo Clinic cohort study of personality and aging.
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DOI：
10.1097/psy.0b013e31819e67db
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发表时间：
2009-06
影响因子：
3.3
通讯作者：
Rocca WA
中科院分区：
文献类型：
--
作者：
Grossardt BR;Bower JH;Geda YE;Colligan RC;Rocca WA
研究人格特征与全因死亡率的关系。我们建立了一个由7216名受试者组成的历史队列，这些受试者于1962年至1965年在马约诊所完成了明尼苏达多相人格调查表（MMPI），并居住在以明尼苏达州罗切斯特为中心的120英里半径范围内。共有7080名受试者（98.1%）接受了40年的主动（通过直接或代理电话访谈）或被动（通过审查病历或获得死亡证明）随访。我们研究了悲观、焦虑和抑郁的人格特征（用MMPI量表测量）与全因死亡率的关系。随访期间共有4634例受试者（65.5%）死亡。在男性和女性中，悲观、焦虑和抑郁的人格特征与全因死亡率的增加有关。此外，我们观察到所有三个量表从第一到第四个四分位数的风险增加的线性趋势。结果是相似的，在额外的分析考虑的人格分数作为连续变量，在分析中结合三个人格特质到一个复合神经质分数，并在几组敏感性分析。即使在生命早期（20至39岁）测量人格，这些关联仍然显着。我们的研究结果表明，与神经质有关的人格特征与全因死亡率增加的风险有关，即使在生命早期进行测量。
To study the association between several personality traits and all-cause mortality. We established a historical cohort of 7216 subjects who completed the Minnesota Multiphasic Personality Inventory (MMPI) for research at the Mayo Clinic from 1962 to 1965, and who resided within a 120-mile radius centered in Rochester, MN. A total of 7080 subjects (98.1%) were followed over four decades either actively (via a direct or proxy telephone interview) or passively (via review of medical records or by obtaining their death certificates). We examined the association of pessimistic, anxious, and depressive personality traits (as measured using MMPI scales) with all-cause mortality. A total of 4634 subjects (65.5%) died during follow-up. Pessimistic, anxious, and depressive personality traits were associated with increased all-cause mortality in both men and women. In addition, we observed a linear trend of increasing risk from the first to the fourth quartile for all three scales. Results were similar in additional analyses considering the personality scores as continuous variables, in analyses combining the three personality traits into a composite neuroticism score, and in several sets of sensitivity analyses. These associations remained significant even when personality was measured early in life (ages 20 to 39 years). Our findings suggest that personality traits related to neuroticism are associated with an increased risk of all-cause mortality even when they are measured early in life.