Long-term visual acuity and the duration of macular detachment: findings from a prospective population-based study
Long-term visual acuity and the duration of macular detachment: findings from a prospective population-based study
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DOI：
10.1136/bjophthalmol-2012-302330
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发表时间：
2013-02-01
影响因子：
4.1
通讯作者：
Singh, Jaswinder
中科院分区：
文献类型：
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作者：
Mitry, Danny;Awan, Muhammad Amer;Singh, Jaswinder
目的报告一项多中心前瞻性招募的黄斑脱离孔源性视网膜脱离（RRD）患者队列的长期视力结果。方法苏格兰视网膜脱离研究是一项前瞻性招募的研究，招募了苏格兰2年期间（2007-2009年）所有原发性RRD的病例。在初次手术后6周、3个月、6个月和1年，邀请来自四个参与研究中心的所有黄斑脱落RRD患者进行临床检查。使用joinpoint模型，我们估计黄斑脱离的持续时间对最终视力outcome.Results的效果，总共有291例黄斑关闭RRD没有预先存在的视网膜疾病谁成功修复后一个操作。65.9%的患者最终视力（VA）达到0.48 logMAR（6/18）。我们的模型确定了两个时间点（第8天（95%CI 3至15天）和（第21天（95%CI 6至26天））后，有一个统计学上显着的恶化，最终VA。结论我们的研究表明，大多数患者的黄斑关闭RRD成功修复一个操作将实现VA的6/18或更好的最终随访。黄斑脱离8天后，最终的视力结果可能会受到不利影响，因此，在此期间进行手术修复是可取的。黄斑脱离的持续时间
Aim To report the long-term visual outcome of a multicentre prospectively recruited cohort of macula-off rhegmatogenous retinal detachments (RRD)Methods The Scottish retinal detachment study was a prospectively recruited study that recruited all incident cases of primary RRD in Scotland over a 2-year period (2007-2009). All patients with a macula-off RRD from four participating sites were invited for clinical examination at 6 weeks, 3 months, 6 months and 1 year after the initial surgery. Using a joinpoint model we estimated the effect of duration of macular detachment on final visual outcome.Results In total, there were 291 patients with macula-off RRD without pre-existing retinal disease who had successful repair after one operation. 65.9% achieved a final visual acuity (VA) of 0.48 logMAR(6/18). Our model identified two time points (day 8 (95% CI 3 to 15 days) and (day 21 (95% CI 6 to 26 days)) after which there was a statistically significant worsening in final VA.Conclusions Our study suggests that the majority of patients with macula-off RRD successfully repaired with one operation will achieve a VA of 6/18 or better at final follow-up. After 8 days of macular detachment, the final visual outcome may be adversely affected and, thus, operative repair within this period is desirable. Duration of macular detachment of