Quantitative assessment of atrial regional function using motion estimation computed tomography.
Quantitative assessment of atrial regional function using motion estimation computed tomography.
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DOI：
10.1097/rct.0000000000000108
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发表时间：
2014-09
影响因子：
1.3
通讯作者：
Taguchi K
中科院分区：
文献类型：
--
作者：
Ashikaga H;Cammin J;Tang Q;Knudsen K;Inoue Y;Fishman EK;Taguchi K
我们验证了一种新的基于图像的运动估计CT技术（iME），以量化在猪体内心房区域功能。家猪（n=8）在正中胸骨切开术前后进行了CT扫描，其中将15-30个玻璃珠缝合到心房以计算运动估计误差。使用iME估计四维运动矢量场（MVF）。计算心房内膜的面积变化率（%AC），以评估表面变形。基于MVF的测量和计算坐标之间的误差为0.76±0.43 mm。%AC具有区域异质性。%AC时程在右心房和左心房之间有显著性差异（P<0.001），在右心耳和右心房之间有显著性差异（P=0.004）。使用iME定量评估心房局部功能是高度准确的。iME可以量化在射血分数等整体功能指数中不明显的细微区域功能障碍。
We validated a novel image-based motion estimation CT technique (iME) to quantify atrial regional function in swine in vivo. Domestic swine (n=8) underwent CT scan with intravenous contrast before and after median sternotomy where 15–30 glass beads were sutured to the atria to calculate the motion estimation error. Four-dimensional motion vector field (MVF) was estimated using iME. Area change ratio (%AC) was calculated over the atrial endocardium to assess the surface deformation. The error between the measured and the calculated coordinates based on MVF was 0.76±0.43 mm. %AC was regionally heterogeneous. %AC time course was significantly different between the right and the left atrium (P<0.001), and between the right atrial appendage and the right atrial chamber (P=0.004). Quantitative assessment of atrial regional function using iME is highly accurate. iME can quantify subtle regional dysfunction that is not apparent in global functional indices such as ejection fraction.