Buprenorphine diversion and injection in Melbourne, Australia: an emerging issue?
Buprenorphine diversion and injection in Melbourne, Australia: an emerging issue?
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DOI：
10.1111/j.1360-0443.2004.00958.x
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发表时间：
2005-02-01
期刊：
影响因子：
6
通讯作者：
Dobbin, M
中科院分区：
文献类型：
--
作者：
Jenkinson, RA;Clark, NC;Dobbin, M
目的了解澳大利亚墨尔本地区注射吸毒者丁丙诺啡转移和注射的相关指标，探讨丁丙诺啡注射的相关因素。设计2002年非法药物报告系统（IDRS）横断面研究的墨尔本分部在澳大利亚墨尔本设置五个针头和注射器项目地点。参与者共15 6名注射吸毒者。研究资格标准是在过去6个月内至少每月注射一次，并且在墨尔本居住至少12个月。测量方法结构化问卷，内容包括人口特征、药物使用历史、药物的价格、纯度和可得性、犯罪活动、冒险行为、与健康有关的问题和一般药物使用趋势。超过三分之一（37%）的研究样本报告在其一生中注射过丁丙诺啡，33%的人报告在过去6个月内注射过丁丙诺啡。最近注射丁丙诺啡与注射其他类型药物（即多种药物注射者）、类阿片替代治疗、与注射有关的健康问题和参与犯罪有关。报告最近注射丁丙诺啡的人中，近一半（47%）报告在此期间至少一次非法获得该药物。结论：考虑到丁丙诺啡静脉注射相关的重大健康危害（如静脉损伤、脓肿和感染、急性停药、血源性病毒传播、住院和死亡），有必要对墨尔本丁丙诺啡滥用情况进行常规监测。这些结果表明，需要制定有效的对策，以解决在这种情况下转移和注射丁丙诺啡的问题。
Aims To examine indicators of buprenorphine diversion and injection among injecting drug users in Melbourne, Australia and to determine the factors associated with buprenorphine injection.Design Melbourne arm of the 2002 Illicit Drug Reporting System (IDRS) cross-sectional studySetting Five Needle and Syringe Programme sites in Melbourne, Australia.Participants A total of 15 6 current injecting drug users (IDU). Study elibility criteria were at least monthly injection during the previous 6 months, and Melbourne residence for at least the preceding 12 months.Measurements Structured questionnaire covering demographic characteristics, drug use history, the price, purity and availability of drugs, criminal activity, risk-taking behaviours, health-related issues and general drug use trends.Findings Over one-third (37'%) of the study sample reported injecting buprenorphine in their life-time and 33%, reported injecting the drug in the last 6 months. Recent buprenorphine injection was associated with the injection of other drug types (i.e. polydrug injectors), opioid substitution treatment, injection-related health problems and involvement in crime. Almost half (47%) of those who reported recent buprenorphine injection reported obtaining the drug illicitly at least once during that time.Conclusions Given the significant health harms associated with intravenous buprenorphine use (e.g. vein damage, abscesses and infections, precipitated withdrawal, blood-borne virus transmission, hospitalization and death), routine monitoring of the misuse of buprenorphine in Melbourne is warranted. These results suggest the need for development of effective countermeasures to address diversion and injection of buprenorphine in this setting.