Interferon: an inducer of macrophage activation by polyanions.
Interferon: an inducer of macrophage activation by polyanions.
复制标题
干扰素:聚阴离子激活巨噬细胞的诱导剂。
作者:
R. Schultz;J. Papamatheakis;M. Chirigos
Purified mouse fibroblast interferon (IF) directly rendered resting macrophages tumoricidal. The physicochemical properties and species specificity of the stimulatory agent fall within the present definition of IF. Since a number of polyanions induce macrophage IF, the antitumor and antimicrobial activities may result from the ability of newly released IF to modify macrophage activity.