Prevalence of vulvar lichen sclerosus in a general gynecology practice.
Prevalence of vulvar lichen sclerosus in a general gynecology practice.
复制标题
一般妇科实践中外阴硬化性苔藓的患病率。
DOI：
--
复制
发表时间：
2005
影响因子：
0.2
通讯作者：
Monica Srodon
中科院分区：
文献类型：
--
作者：
A. Goldstein;S. Marinoff;K. Christopher;Monica Srodon
客观的
OBJECTIVE
To describe the rate of vulvar lichen sclerosus in 1 general gynecology practice.
STUDY DESIGN
A database of 1,675 consecutive patients presenting in a 3-year period to a general gynecology practice was utilized to identify women with lichen sclerosus. Data included age, menopausal status, symptoms and physical examination findings. Pathology specimens were reexamined by a gynecologic pathologist to confirm the diagnosis of lichen sclerosus.
RESULTS
Of the 1,675 patients, 28 (1.7%) had biopsy-proven vulvar lichen sclerosus. Nine patients been diagnosed previously, and 19 were new cases. The mean age at diagnosis was 52.6 years (SD +/- 15.9) versus 37.1 years (SD +/- 16.4) for those without lichen sclerosus (p < 0.001). Fifteen of the 28 patients (54%) were post-menopausal at the time of diagnosis. Of the 19 women with newly diagnosed lichen sclerosus, 8 (42%) were symptomatic. Of the 11 asymptomatic women, 7 (64%) had scarring of the clitoral prepuce or resorption of the labia minora.
CONCLUSION
The rate of vulvar lichen sclerosus in 1 general gynecology private practice is approximately 1.7%. Clinicians must maintain a high index of suspicion to make the diagnosis, as at least one third of patients may be asymptomatic.