MRI-Guided Percutaneous Transpedicular Biopsy of Thoracic and Lumbar Spine Using a 0.23T Scanner With Optical Instrument Tracking
MRI-Guided Percutaneous Transpedicular Biopsy of Thoracic and Lumbar Spine Using a 0.23T Scanner With Optical Instrument Tracking
复制标题
DOI：
10.1002/jmri.24924
复制
发表时间：
2015-12-01
影响因子：
4.4
通讯作者：
Li, Chengli
中科院分区：
文献类型：
--
作者：
Liu, Ming;Sequeiros, Roberto Blanco;Li, Chengli
目的：前瞻性评价0.23T磁共振成像光学跟踪引导下经皮胸腰椎椎弓根穿刺活检的安全性和准确性。材料与方法：67例患者67个胸腰椎病变行0.23T磁共振光学跟踪引导下经皮穿刺活检。这些病变根据位置分为两组：胸椎16处病变和腰椎51处病变。计算诊断准确性、敏感性和特异性，并使用Fisher精确检验对两组进行比较。结果：所有标本均能满足诊断要求。MRI引导下经皮穿刺活检组织学检查显示38例恶性病变和29例良性病变。手术或临床随访的最终诊断为恶性病变42例，良性病变25例。MRI引导下经皮椎弓根胸腰椎穿刺活检诊断恶性肿瘤的综合诊断性能如下：准确性，94%，敏感性，89%，特异性，100%。两组之间无显著差异（P=1，Fisher精确检验）。结论：MRI引导下经皮椎弓根穿刺活检是一种安全、准确的诊断技术，可用于胸腰椎病变的诊断。
Purpose: To prospectively evaluate the safety and accuracy of magnetic resonance imaging (MRI)-guided percutaneous transpedicular biopsy of thoracic and lumbar spine using 0.23T magnetic resonance imaging with optical tracking.Materials and Methods: Sixty-seven thoracic and lumbar spine lesions in 67 patients underwent MRI-guided percutaneous transpedicular biopsy using 0.23T MRI with optical tracking. These lesions were divided into two groups according to the location: 16 lesions in the thoracic spine and 51 lesions in the lumbar spine. The diagnostic accuracy, sensitivity, and specificity were calculated, and comparison of the two groups was performed using Fisher's exact test. Each patient was monitored for complications.Results: All specimens obtained were sufficient for diagnosis. Histological examination of MRI-guided percutaneous biopsy revealed 38 malignant and 29 benign lesions. The final diagnoses from surgery or clinical follow-up were 42 malignant lesions and 25 benign lesions. The combined diagnostic performance of MRI-guided percutaneous transpedicular thoracic and lumbar biopsy in diagnosing malignant tumors was as follows: accuracy, 94%; sensitivity, 89%; and specificity, 100%. There was no significant difference between the two groups (P=1, Fisher's exact test). No serious complications occurred.Conclusion: MRI-guided percutaneous transpedicular biopsy is a safe and accurate diagnostic technique to evaluate thoracic and lumbar spine lesions.