Autophagy-Sensitized Cytotoxicity of Quantum Dots in PC12 Cells
Autophagy-Sensitized Cytotoxicity of Quantum Dots in PC12 Cells
复制标题
PC12 细胞中量子点的自噬敏化细胞毒性
DOI：
10.1002/adhm.201300294
复制
发表时间：
2014-03-01
影响因子：
10
通讯作者：
Huang, Qing
中科院分区：
文献类型：
--
作者：
Li, Xiaoming;Chen, Nan;Huang, Qing
Both CdTe and CdTe/CdS/ZnS quantum dots induce similar levels of autophagy in PC12 and HEK293 cells, while the former exhibits higher toxicity. Low levels of cadmium ions are not sufficient to induce either autophagy or cytotoxicity by themselves. Interestingly, the combination of cadmium ions and CdTe/CdS/ZnS mimics the toxic effect of CdTe, suggesting that autophagy sensitizes cells to cadmium ions.
