Osteoarthritis

Osteoarthritis
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DOI:
10.1016/j.berh.2010.11.001
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发表时间:
2010-12-01
影响因子:
5.2
通讯作者:
Fransen, Marlene
Fransen, Marlene
中科院分区:
医学2区
文献类型:
--
作者:
Busija, Lucy;Bridgett, Lisa;Fransen, Marlene

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在国际上,骨关节炎的患病率估计显示出广泛的变异性,这取决于研究人群的年龄和性别、所使用的病例识别方法以及所包括的关节部位的特异性。目前,在流行病学研究中没有公认的“金标准”来识别骨关节炎病例。尽管缺乏标准化,但全球基于人群的研究一致表明,骨关节炎患病率与年龄增加呈正相关,最大的疾病负担可归因于髋关节或膝关节的受累。为了估计涉及髋关节或膝关节的骨关节炎的真实负担,需要全面考虑所有相关的发病率。需要确定疾病发生和进展的可改变的风险因素。(C)2010爱思唯尔有限公司保留所有权利。
Internationally, prevalence estimates for osteoarthritis show wide variability depending on the age and sex of the studied population, the method of case identification used, and the specificity of joint sites included. Currently, there is no generally agreed "gold standard" for identifying cases of osteoarthritis in epidemiologic studies. Despite this lack of standardisation, it is consistently demonstrated in population-based studies, worldwide, that osteoarthritis prevalence is positively associated with increasing age and that the greatest disease burden is attributable to involvement of the hip or knee joints. To estimate the true burden of osteoarthritis involving the hips or knees, comprehensive accounting of all associated morbidity is required. The identification of modifiable risk factors for disease incidence and progression is needed. (C) 2010 Elsevier Ltd. All rights reserved.