Incidence and prediction of falls in Parkinson's disease: a prospective multidisciplinary study
Incidence and prediction of falls in Parkinson's disease: a prospective multidisciplinary study
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DOI：
10.1136/jnnp.72.6.721
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发表时间：
2002-06-01
影响因子：
11
通讯作者：
Walker, RW
中科院分区：
文献类型：
--
作者：
Wood, BH;Bilclough, JA;Walker, RW
目的：准确确定帕金森病（PD）患者福尔斯的发生率，并从基线数据中研究跌倒的预测风险因素。方法：根据脑库标准诊断的109例特发性PD受试者接受了多学科基线评估，包括人口统计学和历史数据、疾病特异性评级量表、物理治疗评估、视觉、心血管和自主神经功能测试，和骨密度测定。然后前瞻性地随访患者一年，每周使用预付费明信片沿着电话followup.Results：福尔斯发生在68.3%的科目。既往福尔斯跌倒史、病程、痴呆和手臂摆动丧失是跌倒的独立预测因素。疾病严重程度，平衡障碍，抑郁症，和falling.Conclusions之间也有显着的关联：福尔斯是一个常见的问题，在PD和一些主要的危险因素是潜在的修改。未来的研究需要着眼于预防PD患者福尔斯跌倒的干预措施。
Objectives: To accurately establish the incidence of falls in Parkinson's disease (PD) and to investigate predictive risk factors for fallers from baseline data.Methods: 109 subjects with idiopathic PD diagnosed according to the brain bank criteria underwent a multidisciplinary baseline assessment comprising demographic and historical data, disease specific rating scales, physiotherapy assessment, tests of visual, cardiovascular and autonomic function, and bone densitometry. Patients were then prospectively followed up for one year using weekly prepaid postcards along with telephone follow up.Results: Falls occurred in 68.3% of the subjects. Previous falls, disease duration, dementia, and loss of arm swing were independent predictors of falling. There were also significant associations between disease severity, balance impairment, depression, and falling.Conclusions: Falls are a common problem in PD and some of the major risk factors are potentially modifiable. There is a need for future studies to look at interventions to prevent falls in PD.