When keeping in mind supports later bringing to mind: Neural markers of phonological rehearsal predict subsequent remembering
When keeping in mind supports later bringing to mind: Neural markers of phonological rehearsal predict subsequent remembering
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DOI：
10.1162/089892901753294356
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发表时间：
2001-11-15
影响因子：
3.2
通讯作者：
Wagner, AD
中科院分区：
文献类型：
--
作者：
Davachi, L;Maril, A;Wagner, AD
回想起过去经历的能力取决于经历过程中参与并支持记忆形成的认知和神经过程。一个备受争议的核心问题是，死记硬背的言语排练背后的过程（即将信息保留在头脑中的工作记忆机制）是否会影响记忆的形成和随后的记忆。本研究使用事件相关的功能磁共振成像（fMRI）来探讨工作记忆维护操作与长期记忆之间的关系。具体来说，我们研究了支持在线维护语言代码的神经区域的激活程度是否可以预测学习过程中死记硬背单词的后续记忆。此外，在死记硬背过程中，评估了与语义检索相关区域的神经激活程度，以确定附带语义阐述在后续记忆中可能发挥的作用。死记硬背的项目。结果显示，（a）先前与语音排练相关的神经区域（左前额叶、双侧顶叶、辅助运动和小脑区域）的激活程度与随后的记忆相关；（b）虽然死记硬背平均而言不会引起与语义检索相关的左前额叶前区的激活，但对于随后更好地记住的试验，该区域的激活更大。与死记硬背不会影响学习的普遍观点相反，这些数据表明，除了语义阐述之外，语音维持机制还支持对体验的编码，以便以后可以记住它。
The ability to bring to mind a past experience depends on the cognitive and neural processes that are engaged during the experience and that support memory formation. A central and much debated question is whether the processes that underlie rote verbal rehearsal-that is, working memory mechanisms that keep information in mind-impact memory formation and subsequent remembering. The present study used event-related functional magnetic resonance imaging (fMRI) to explore the relation between working memory maintenance operations and long-term memory, Specifically, we investigated whether the magnitude of activation in neural regions supporting the on-line maintenance of verbal codes is predictive of subsequent memory for words that were rote-rehearsed during learning, Furthermore, during rote rehearsal, the extent of neural activation in regions associated with semantic retrieval was assessed to determine the role that incidental semantic elaboration may play in subsequent memory for rote-rehearsed items. Results revealed that (a) the magnitude of activation in neural regions previously associated with phonological rehearsal (left prefrontal, bilateral parietal, supplementary motor, and cerebellar regions) was correlated with subsequent memory and (b) while rote rehearsal did not-on average-elicit activation in an anterior left prefrontal region associated with semantic retrieval, activation in this region was greater for trials that were subsequently better remembered. Contrary to the prevalent view that rote rehearsal does not impact learning, these data suggest that phonological maintenance mechanisms, in addition to semantic elaboration, support the encoding of an experience such that it can be later remembered.