Changes in Functional Magnetic Resonance Imaging Cortical Activation with Cross Education to an Immobilized Limb
Changes in Functional Magnetic Resonance Imaging Cortical Activation with Cross Education to an Immobilized Limb
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DOI：
10.1249/mss.0b013e318210783c
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发表时间：
2011-08-01
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影响因子：
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通讯作者：
Borowsky, Ron
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文献类型：
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作者：
Farthing, Jonathan P.;Krentz, Joel R.;Borowsky, Ron
法辛，J. P.，J. R.克伦茨角R.马格努斯S.巴斯拉诺瓦兹埃索彭科湾E. SARTY和R.鲍罗斯基。功能性磁共振成像皮层激活与固定肢体交叉训练的变化。医学科学体育锻炼，第43卷，第8期，第100页。1394-1405，2011年。目的：本研究的目的是评估皮质激活与交叉教育的影响，以固定的肢体，使用功能性磁共振成像。方法：14名右利手参与者被分配到两组。一组（n = 7）佩戴石膏并对自由臂进行力量训练（CAST-TRAIN）。第二组（n = 7）戴石膏，不进行力量训练（CAST）。石膏被应用于非优势（左）手腕和手。力量训练为右手最大等长握肌收缩5d.wk（-1）。在干预前后评估峰值力（握力计）、肌肉厚度（超声）、EMG和皮质激活（功能性磁共振成像）。结果：CAST-TRAIN可提高右手握力10.7%（P < 0.01），而肌肉厚度无明显变化。固定臂的力量有显著的组×时间交互作用（P < 0.05）。CAST-TRAIN组固定臂握力基本保持不变，而CAST组固定臂握力下降11%（P < 0.05）。所有参与者固定手臂的肌肉厚度平均降低了3.3%（P < 0.05），在调整基线差异后，两组之间没有差异。EMG激活存在显著的组x时间相互作用（P < 0.05），其中CAST-TRAIN显示出增加趋势，CAST显示出降低趋势，两组合并。对于CAST-TRAIN固定臂，训练后对侧运动皮层激活显著增加（P < 0.05）。对于CAST的固定臂，运动皮层激活没有变化。结论：自由肢的握力训练可减轻单侧制动时的力量损失。通过交叉教育效应保持固定肢体的力量可能与运动皮层激活增加有关。
FARTHING, J. P., J. R. KRENTZ, C. R. MAGNUS, T. S. BARSS, J. L. LANOVAZ, J. CUMMINE, C. ESOPENKO, G. E. SARTY, and R. BOROWSKY. Changes in Functional Magnetic Resonance Imaging Cortical Activation with Cross Education to an Immobilized Limb. Med. Sci. Sports Exerc., Vol. 43, No. 8, pp. 1394-1405, 2011. Purpose: The purpose of this study was to assess cortical activation associated with the cross-education effect to an immobilized limb, using functional magnetic resonance imaging. Methods: Fourteen right-handed participants were assigned to two groups. One group (n = 7) wore a cast and strength trained the free arm (CAST-TRAIN). The second group (n = 7) wore a cast and did not strength train (CAST). Casts were applied to the nondominant (left) wrist and hand. Strength training was maximal isometric handgrip contractions (right hand) 5 d.wk(-1). Peak force (handgrip dynamometer), muscle thickness (ultrasound), EMG, and cortical activation (functional magnetic resonance imaging) were assessed before and after the intervention. Results: CAST-TRAIN improved right handgrip strength by 10.7% (P < 0.01) with no change in muscle thickness. There was a significant group x time interaction for strength of the immobilized arm (P < 0.05). Handgrip strength of the immobilized arm of CAST-TRAIN was maintained, whereas the immobilized arm of CAST significantly decreased by 11% (P < 0.05). Muscle thickness of the immobilized arm decreased by an average of 3.3% (P < 0.05) for all participants and was not different between groups after adjusting for baseline differences. There was a significant group x time interaction for EMG activation (P < 0.05), where CAST-TRAIN showed an increasing trend and CAST showed a decreasing trend, pooled across arms. For the immobilized arm of CAST-TRAIN, there was a significant increase in contralateral motor cortex activation after training (P < 0.05). For the immobilized arm of CAST, there was no change in motor cortex activation. Conclusions: Handgrip strength training of the free limb attenuated strength loss during unilateral immobilization. The maintenance of strength in the immobilized limb via the cross-education effect may be associated with increased motor cortex activation.