Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets

Saccharides and temperature dual-responsive hydrogel layers for harvesting cell sheets
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用于收获细胞片的糖和温度双响应水凝胶层。

DOI:
10.1039/c4cc08183h
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发表时间:
2015-01-01
影响因子:
4.9
通讯作者:
Yang, Huilin
Yang, Huilin
中科院分区:
化学2区
文献类型:
--
作者:
Guo, Bingbing;Pan, Guoqing;Yang, Huilin

文献摘要

被引文献

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基于含有苯基硼酸(PBA)基团的PNIPAAm共聚物制备了二酰亚胺和温度双重响应水凝胶,并用于收获细胞片层。细胞片可以在37 ℃下简单地通过增加糖浓度从水凝胶层释放,并且可以在较低温度和升高的糖浓度下更有效地释放。
Saccharides and temperature dual-responsive hydrogels have been prepared based on PNIPAAm copolymers containing phenylboronic acid (PBA) groups and used for harvesting cell sheets. The cell sheet could be released from the hydrogel layer at 37 degrees C simply by increasing sugar concentration, and could be more efficiently released at a lower temperature and elevated sugar concentration.