Efficacy of learning through play plus intervention to reduce maternal depression in women with malnourished children: A randomized controlled trial from Pakistan
Efficacy of learning through play plus intervention to reduce maternal depression in women with malnourished children: A randomized controlled trial from Pakistan
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DOI：
10.1016/j.jad.2020.09.001
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发表时间：
2021-01-01
影响因子：
6.6
通讯作者：
Chaudhry, Nasim
中科院分区：
文献类型：
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作者：
Husain, Nusrat;Kiran, Tayyeba;Chaudhry, Nasim
背景：与孕产妇抑郁和儿童营养不良相关的危险因素和不良后果是包括巴基斯坦在内的低收入和中等收入国家（LMIC）发病率和死亡率的主要原因。超过25%的妇女患有产妇抑郁症。多达50%的儿童营养不良，占该国所有5岁以下儿童死亡人数的35%。目的：探讨“玩中学习+思维健康计划”（LTP Plus）干预对营养不良儿童母亲抑郁的影响。方法：在这个随机对照试验中，所有到儿科就诊的符合条件的母亲都被邀请参加研究。在总共256名母亲中，包括107名，其中54名随机分配到LTP +组，53名随机分配到常规治疗组（TAU）。采用爱丁堡产后抑郁量表（EPDS）进行抑郁筛查。采用汉密尔顿抑郁评定量表（HDRS）、母亲依恋量表（MAI）、社会支持量表（OSLO-3）和Euro-QoL （EQ-5D）测量抑郁严重程度、母子依恋、支持水平和健康相关生活质量维度。评估分别在基线、干预结束（距基线3个月）和距基线6个月完成。结果：LTP Plus组母亲的抑郁症状明显改善(p
Background: The risk factors and adverse outcomes related to maternal depression and child malnutrition are a leading cause of morbidity and mortality in low and middle-income countries (LMIC) including Pakistan. Above 25% of women suffer from maternal depression. Up to 50% children are under-nourished which contributes to 35% of all under-5 deaths in the country.Aim: To determine the efficacy of Learning through Play Plus Thinking Healthy Program (LTP Plus) intervention to reduce maternal depression in mothers with undernourished children.Methods: In this randomised controlled trial, all eligible mothers presenting to the paediatric departments were invited to participate in the study. Out of the total 256 mothers screened, 107 were included, 54 of those were randomly allocated to LTP Plus group and 53 to treatment as usual (TAU). Edinburgh Postnatal Depression Scale (EPDS) was used to screen for depression. Hamilton Depression Rating Scale (HDRS), Maternal Attachment Inventory (MAI), Social Support Scale (OSLO-3) and the Euro-QoL (EQ-5D) were used to measure the severity of depression, mother-child attachment, level of support and health related quality of life dimensions. Assessments were completed at baseline, end of intervention (3 months from baseline) and at 6 months from baseline.Results: Mothers in the LTP Plus group significantly showed improvements in depression (p