Higher C-reactive protein concentration and white blood cell count in subjects with more coronary risk factors and/or lower physical fitness among apparently healthy Japanese

Higher C-reactive protein concentration and white blood cell count in subjects with more coronary risk factors and/or lower physical fitness among apparently healthy Japanese
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DOI:
10.1253/circj.66.677
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发表时间:
2002-07-01
影响因子:
3.3
通讯作者:
Nagata, K
Nagata, K
中科院分区:
医学3区
文献类型:
--
作者:
Ichihara, Y;Ohno, J;Nagata, K

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在爱知县保健中心接受健康检查的2722人(男性1,876人,平均年龄:51.3+/-10.3岁;女性846人,平均年龄:51.4+/-11.1)中,研究了C反应蛋白(CRP)浓度和白细胞计数(WBC)与冠状动脉危险因素数量、最大摄氧量(VO2max)四分位数和身体健康评分的关系。C反应蛋白测定采用常规乳胶免疫比浊法。危险因素越多,C反应蛋白和WBC越高。在男性中,只有一个危险因素(RF1)的CRP值最低为0.07 mg/dl,Rf6组的最高值为0.29 mg/dl(P
Of 2,722 people (1,876 men, mean age: 51.3+/-10.3 years; 846 women, mean age: 51.4+/-11.1) who underwent the fitness check program at Aichi Prefectural Center for Health Care, the concentration of C-reactive protein (CRP) and the white blood cell count (WBC) were investigated in relation to the number of coronary risk factors, maximum oxygen uptake (VO2max) quartiles and physical fitness score. CRP was measured by conventional latex immunoturbidimetric assay. Both CRP and WBC were higher in those who had more risk factors. In men the lowest mean CRP was 0.07 mg/dl in those with only one risk factor (RF1) and the highest was 0.29 mg/dl in RF6 (p