Psychoendocrine Study of Adaptation in Young Hemophiliacs
Psychoendocrine Study of Adaptation in Young Hemophiliacs
复制标题
青年血友病患者适应的心理内分泌研究
作者：
Å. Mattsson;S. Gross;T. Hall
&NA;10名血友病男孩参加了一项关于心理社会适应和皮质类固醇排泄模式的长期研究。方法包括墨迹测试测量身体图像边界，行为评级和尿17-OHCS水平的测定。后两项在家中、研究中心和出血发作期间的儿科病房进行。组平均17-OHCS水平（mg/ 24小时/平方米）在家中最低，在研究中心较高，在病房最高。在所有情况下，每例受试者倾向于保持其在组内的相对17-OHCS水平等级。适应良好的血友病患者认为他们的身体边界是明确的，并且始终是高17-OHCS排泄物，这表明相对较高的生理唤醒。差的适应者是低排泄者。适应程度和肾上腺皮质活动之间的正相关性进行了评估，在类型的自我防御和应对机制和缓冲与疾病相关的情绪困扰的有效性。
&NA; Ten hemophilic boys participated in a long‐term study of psychosocial adaptation and corticosteroid excretion pattern. Methods included inkblot test measurements of body‐image boundaries, behavioral ratings, and determinations of urinary 17‐OHCS levels. The latter two were performed at home, in a research center, and on a pediatric ward during bleeding episodes. Group mean 17‐OHCS level (mg/ 24 hr per square meter) was lowest at home, higher in the research center, and highest on the ward. Each subject tended to hold his relative 17‐OHCS level rank within the group in all settings. The well adapted hemophiliacs viewed their body boundaries as definite, and were consistently high 17‐OHCS excretors, suggesting relatively high physiologic arousal. The poor adapters were low excretors. The positive correlation between degree of adaptation and adrenal cortical activity was evaluated in terms of types of ego defensive and coping mechanisms and their effectiveness in buffering emotional distress associated with the illness.