Simultaneous Biodetoxification of S, N, and O Pollutants by Engineering of a Carbazole-Degrading Gene Cassette in a Recombinant Biocatalyst
Simultaneous Biodetoxification of S, N, and O Pollutants by Engineering of a Carbazole-Degrading Gene Cassette in a Recombinant Biocatalyst
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DOI：
10.1128/aem.01374-06
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发表时间：
2006-08
影响因子：
4.4
通讯作者：
Bo Yu;Cuiqing Ma;Wenjuan Zhou;Shanshan Zhu;Ying Wang;Jingyao Qu;Fuli Li;P. Xu
中科院分区：
文献类型：
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作者：
Bo Yu;Cuiqing Ma;Wenjuan Zhou;Shanshan Zhu;Ying Wang;Jingyao Qu;Fuli Li;P. Xu
摘要将编码咔唑降解为邻氨基苯甲酸的酶的基因盒引入二苯并噻吩类降解剂中。产生的红球红球菌XPDN能够同时将模型污染物二苯并噻吩苯、咔唑和二苯并呋喃转化为无毒的代谢物，可能具有生物修复的应用潜力。
ABSTRACT The gene cassette encoding enzymes responsible for degrading carbazole to anthranilic acid was introduced into a dibenzothiophene degrader. The resultant strain, Rhodococcus erythropolis XPDN, could simultaneously transform the model pollutants dibenzothiophene, carbazole, and dibenzofuran to nontoxic metabolites and may have an application potential for bioremediation.