Entomological surveillance of behavioural resilience and resistance in residual malaria vector populations
Entomological surveillance of behavioural resilience and resistance in residual malaria vector populations
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DOI：
10.1186/1475-2875-12-124
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发表时间：
2013-04-11
期刊：
影响因子：
3
通讯作者：
Killeen, Gerry F.
中科院分区：
文献类型：
--
作者：
Govella, Nicodem J.;Chaki, Prosper P.;Killeen, Gerry F.
背景资料：最强的疟疾病媒严重依赖人血，因此很容易受到驱虫蚊帐和室内滞留喷洒的攻击。蚊子类群，可以避免喂养或在室内休息，或通过从动物身上获得血液，介导越来越多的比例不断减少的传播，持续作为杀虫剂处理过的蚊帐和室内滞留喷雾杀虫剂是scaledup.Presentation的假设：增加频率的行为逃避性状内持续残留的载体系统通常反映了最有效的和最脆弱的载体类群室内滞留喷雾杀虫剂或驱虫蚊帐的成功抑制，而不是他们的失败。在扩大干预规模后，蚊子行为模式的许多常见变化可以很好地解释为改变了分类组成和表型可塑性行为偏好的表达，而不是改变了个体或种群的先天偏好。对当代证据基础的详细审查尚未提供任何明确的真实行为抵抗的例子，因此，假设的影响：在过度解释大多数现有报告之前，应谨慎行事，这些报告称，蚊子能够逃避致命的杀虫剂接触的行为特征频率增加：这可能仅仅是抑制构成原始传播系统的最易受行为伤害的病媒分类群的结果。一直表现出这种逃避特征的苔藓分类群可能更准确地描述为行为弹性，而不是抵抗。目前正在进行的国家或区域昆虫学杀虫剂生理敏感性监测调查，应辅之以对疟疾病媒种群动态和决定干预影响的行为表型进行具有生物学和流行病学意义的估计，以便设计、选择、评价和优化病媒控制措施的实施。
Background: The most potent malaria vectors rely heavily upon human blood so they are vulnerable to attack with insecticide-treated nets (ITNs) and indoor residual spraying (IRS) within houses. Mosquito taxa that can avoid feeding or resting indoors, or by obtaining blood from animals, mediate a growing proportion of the dwindling transmission that persists as ITNs and IRS are scaled up.Presentation of the hypothesis: Increasing frequency of behavioural evasion traits within persisting residual vector systems usually reflect the successful suppression of the most potent and vulnerable vector taxa by IRS or ITNs, rather than their failure. Many of the commonly observed changes in mosquito behavioural patterns following intervention scale-up may well be explained by modified taxonomic composition and expression of phenotypically plastic behavioural preferences, rather than altered innate preferences of individuals or populations.Testing the hypothesis: Detailed review of the contemporary evidence base does not yet provide any clear-cut example of true behavioural resistance and is, therefore, consistent with the hypothesis presented.Implications of the hypothesis: Caution should be exercised before over-interpreting most existing reports of increased frequency of behavioural traits which enable mosquitoes to evade fatal contact with insecticides: this may simply be the result of suppressing the most behaviourally vulnerable of the vector taxa that constituted the original transmission system. Mosquito taxa which have always exhibited such evasive traits may be more accurately described as behaviourally resilient, rather than resistant. Ongoing national or regional entomological monitoring surveys of physiological susceptibility to insecticides should be supplemented with biologically and epidemiologically meaningfully estimates of malaria vector population dynamics and the behavioural phenotypes that determine intervention impact, in order to design, select, evaluate and optimize the implementation of vector control measures.