Antibacterial activities of the chemical constituents of Schizophyllum commune MST7-3 collected from coal area
Antibacterial activities of the chemical constituents of Schizophyllum commune MST7-3 collected from coal area
复制标题
煤区裂褶菌MST7-3化学成分的抑菌活性
DOI：
10.1080/14786419.2021.2010075
复制
发表时间：
2021-11-23
影响因子：
2.2
通讯作者：
Xu, Guo-Bo
中科院分区：
文献类型：
--
作者：
Chen, Guang-Gui;Zhu, Qin-Feng;Xu, Guo-Bo
从裂褶菌MST7-3的代谢产物中分离得到2个呋喃丹类化合物(6和7)和5个新化合物(1-5)，以及其他9个已知化合物(8-16)。通过波谱分析，确定了它们的结构。用Mosher方法和旋光度确定了化合物2和3的绝对构型。化合物6和7对嗜麦芽窄食单胞菌有较强的抗菌活性，其MIC值分别为4mU g/m L和16 m u g/m L。
Two fusidane-type active compounds (6 and 7) and five new ones (1-5), along with other nine known compounds (8-16) were isolated from the metabolites of Schizophyllum commune MST7-3. Their structures were elucidated on the basis of spectroscopic analysis. The absolute configurations of compounds 2 and 3 were established by Mosher's method and optical rotation. Compounds 6 and 7 showed significant antibacterial activities against Stenotrophomonas maltophilia with MIC values of 4 mu g/mL and 16 mu g/mL, respectively.