Somatostatin-like immunoreactivity in the region of the prepacemaker nucleus in weakly electric knifefish, Eigenmannia: a quantitative analysis.
Somatostatin-like immunoreactivity in the region of the prepacemaker nucleus in weakly electric knifefish, Eigenmannia: a quantitative analysis.
复制标题
弱电刀鱼 Eigenmannia 前起搏器核区域的生长抑素样免疫反应性：定量分析。
DOI：
10.1016/0006-8993(91)90009-k
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发表时间：
1991
期刊：
影响因子：
2.9
通讯作者：
Heiligenberg,W
中科院分区：
文献类型：
--
作者：
Zupanc,GK;Maler,L;Heiligenberg,W
间脑前起搏核 (PPn) 是一个双侧神经元簇，控制弱电刀鱼 Eigenmannia 中非常规则的电器官放电周期的频率调制。超微结构证据表明，接触 PPn 神经元的兴奋性和抑制性突触的作用受到神经肽的调节。在这项研究中，我们检查了 PPn 区域中生长抑素样免疫反应 (S-IR) 结构的分布。在横向切片中，我们在 PPn 区域发现了 5 个双边 S-IR 结构：“背水平条纹”； “侧细胞群”； “斜条纹”； “结核状条纹”；和“下丘脑条纹”。背水平条纹由 S-IR 纤维、末端和单侧约 200 个细胞体组成，从丘脑背后核和中央后核的第三脑室边缘延伸至 PPn 横向约 400 μm。 S-IR 细胞体在该条纹内显示出独特的分布模式。几乎一半的体细胞位于心室 50 μm 范围内。这些心室细胞很小并且通常密集聚集。横向上，朝向 PPn，标记细胞的数量减少，而它们的大小逐渐增加。外侧细胞群由位于感觉亚核内侧区域的大约 20 个体细胞组成。斜条纹的纤维从下丘脑背侧传播到 PPn。结节条纹的纤维起源于后结节室周核内侧区的S-IR细胞体，并与斜条纹合并。下丘脑条纹的纤维连接下丘脑外侧和对角条纹。成熟雌性下丘脑条纹中的免疫标记密度显着高于未成熟雌性。
The diencephalic prepacemaker nucleus (PPn) is a bilateral cluster of neurons that controls frequency modulations of the otherwise very regular electric organ discharge cycle in weakly electric knifefish,Eigenmannia. Ultrastructural evidence had suggested that the action of excitatory and inhibitory synapses contacting PPn neurons is modulated by neuropeptides. In this investigation, we examined the distribution of somatostatin-like immunoreactive (S-IR) structures in the region of the PPn. In transverse sections, we found 5 bilateral S-IR structures in the region of the PPn: a ‘dorsohorizontal stripe’; a ‘lateral cell group’; a ‘diagonal stripe’; a ‘tubercular stripe’; and a ‘hypothalamic stripe’. The dorsohorizontal stripe, consisting of S-IR fibers, terminals, and roughly 200 cell bodies unilaterally, stretches from the edge of the third ventricle at the thalamic dorsal-posterior nucleus and the central posterior nucleus approximately 400 μm laterally to the PPn. S-IR cell bodies show a distinct pattern of distribution within this stripe. Almost half of the somata are located within 50 μm of the ventricle. These ventricular cells are small and often densely clustered. Laterally, towards the PPn, the number of labelled cells decreases, whereas their size gradually increases. The lateral cell group consists of roughly 20 somata in the medial region of the subelectrosensorius nucleus. Fibers of the diagonal stripe travel from the hypothalamus dorsalis to the PPn. Fibers of the tubercular stripe originate from S-IR cell bodies in the medial zone of the periventricular nucleus of the posterior tuberculum and merge with the diagonal stripe. Fibers of the hypothalamic stripe connect the hypothalamus lateralis and the diagonal stripe. The density of immunolabelling in the hypothalamic stripe is significantly higher in mature than in immature females.