Development and roles of collagenous matrices in the embryonic avian cornea.
Development and roles of collagenous matrices in the embryonic avian cornea.
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胚胎禽角膜中胶原基质的发育和作用。
DOI：
10.1016/s1350-9462(97)00010-4
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发表时间：
1998
影响因子：
17.8
通讯作者：
Birk,DE
中科院分区：
文献类型：
--
作者：
Linsenmayer,TF;Fitch,JM;Gordon,MK;Cai,CX;Igoe,F;Marchant,JK;Birk,DE
角膜发育需要大量胶原基质的产生、组装，有时甚至需要替换。鸡胚角膜是良好的特点，并提供了一定的优势，研究这些矩阵的组装和作用。我们将首先描述要检查的矩阵。这些包括角膜基质本身，首先形成为初级基质，随后形成为次级（成熟）基质;鲍曼膜;德斯密膜;和上皮细胞附着复合体的半桥粒。然后，我们将描述所涉及的胶原类型的特征，包括：纤维胶原（I型，II型和V型），纤维相关胶原（IX型，XII型和XIV型），以及半桥粒的跨膜胶原（XVII型）。然后，在随后的每一节中，我们将详细研究每种胶原基质的结构、组装和发育，以及每种特定的胶原和/或胶原的组合如何被认为为基质提供其独特的性质。这里介绍的工作和观点主要来自我们自己的实验室。因此，这篇文章并不意味着是一个全面的文献综述。对于其他人的相关参考，如果可能的话，我们将引用最近的评论。
Corneal development requires the production, assembly and sometimes replacement of a number of collagenous matrices. The embryonic chick cornea is well-characterized and offers certain advantages for studying the assembly and roles of these matrices. We will first describe the matrices to be examined. These include the corneal stroma proper, first formed as the primary stroma and subsequently as the secondary (mature) stroma; Bowman's Membrane; Descemet's Membrane; and the hemidesmosome of the epithelial cell attachment complex. We will then describe the characteristics of the collagen types involved, including: the fibrillar collagens (types I, II and V), the fibril-associated collagens (types IX, XII and XIV), and the transmembrane collagen of the hemidesmosome (type XVII). Then, in each subsequent section we will examine in detail the structure, assembly and development of each collagenous matrix, and how each specific collagen and/or combination of collagens are thought to provide the matrices with their unique properties. The work and views presented here are largely from our own laboratories. Thus, this article is not meant to be a comprehensive review of the literature. For pertinent references by others, when possible, we will cite recent reviews.