Alignment of physical and genetic maps of human 8q23-qter using somatic cell hybrid mapping panel.

Alignment of physical and genetic maps of human 8q23-qter using somatic cell hybrid mapping panel.
复制标题

使用体细胞混合作图面板对人类 8q23-qter 的物理和遗传图谱进行比对。

DOI:
10.1007/bf02290684
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发表时间:
1994
期刊:
Somatic cell and molecular genetics
影响因子:
--
通讯作者:
Wells,DE
Wells,DE
中科院分区:
--
文献类型:
--
作者:
Parrish,JE;Wang,Y;Wagner,MJ;Wells,DE

文献摘要

相似文献

我们描述了一个由携带人类8号染色体缺失和易位衍生物的人-仓鼠杂交细胞系组成的8q23-qter区域的图谱。该小组将染色体的这一区域划分为9个间隔,并通过Southern blot杂交和PCR绘制了40个位点。使用这个绘图面板使我们能够将8号染色体的两个不同遗传图谱的末端部分彼此对齐,并与染色体的物理图谱对齐。
We describe a mapping panel for the 8q23-qter region composed of human-hamster hybrid cell lines carrying deletion and translocation derivatives of human chromosome 8. The panel divides this region of the chromosome into nine intervals and has beenused to map 40 loci by Southern blot hybridization and PCR. Use of this mapping panel has allowed us to align the terminal portions of two different genetic maps of chromosome 8 with each other and with the physical map of the chromosome.