Functional Magnetic Resonance Imaging Methods.
Functional Magnetic Resonance Imaging Methods.
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DOI：
10.1007/s11065-015-9294-9
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发表时间：
2015-09
影响因子：
5.8
通讯作者：
Glover GH
中科院分区：
文献类型：
--
作者：
Chen JE;Glover GH
自 1992 年问世以来，功能磁共振成像 (fMRI) 已成为研究健康和功能失调大脑认知的不可或缺的工具。 FMRI 监测脑组织氧合的变化，这些变化是由于基于任务的诱发神经反应或在没有意识心理状态（“静息状态”）的情况下神经活动的自发波动而导致的新陈代谢改变而引起的。基于任务的研究揭示了许多重要认知过程的神经相关性，而在静息状态下进行的功能磁共振成像研究则证明了全脑网络是由具有同步、明显自发活动的大脑区域产生的。在本文中，我们回顾了用于采集和分析功能磁共振成像信号的方法。
Since its inception in 1992, Functional Magnetic Resonance Imaging (fMRI) has become an indispensible tool for studying cognition in both the healthy and dysfunctional brain. FMRI monitors changes in the oxygenation of brain tissue resulting from altered metabolism consequent to a task-based evoked neural response or from spontaneous fluctuations in neural activity in the absence of conscious mentation (the “resting state”). Task-based studies have revealed neural correlates of a large number of important cognitive processes, while fMRI studies performed in the resting state have demonstrated brain-wide networks that result from brain regions with synchronized, apparently spontaneous activity. In this article, we review the methods used to acquire and analyze fMRI signals.