Author Correction: Distinguishing genetic correlation from causation across 52 diseases and complex traits.
Author Correction: Distinguishing genetic correlation from causation across 52 diseases and complex traits.
复制标题
作者更正：区分 52 种疾病和复杂性状的遗传相关性和因果关系。
DOI：
10.1038/s41588-018-0296-4
复制
发表时间：
2018
期刊：
影响因子：
30.8
通讯作者：
Price,AlkesL
中科院分区：
文献类型：
--
作者：
O'Connor,LukeJ;Price,AlkesL
在本文最初发布的版本中，方法部分第二段的文本中有两个错误。在“为了识别导致医生诊断的哮喘和过敏性疾病的遗传变异（补充说明中描述的详细表型信息）并将其与其他病症联系起来，我们使用英国生物银行参与者的表型测量（N = 487,409）进行了 GWAS”这句话中，参与者的数量应该是 150,509。在“因此，总共 110,361 名具有高质量基因分型和完整表型/协变量数据的欧洲后裔被用于这些分析，其中包括 25,685 名过敏性疾病受试者（花粉热/过敏性鼻炎或湿疹，无医生诊断的哮喘）、14,085 名哮喘受试者和 76,768 名对照用于分析”短语“没有医生诊断的哮喘”应该读作“一些患有医生诊断的哮喘”。文章的 HTML 和 PDF 版本中的错误已得到纠正。
In the version of this article originally published, there were two errors in the text of the second paragraph of the Methods section. In the sentence “To identify genetic variants that contribute to doctor-diagnosed asthma and allergic diseases (detailed phenotype information described in the Supplementary Note) and link them with other conditions, we performed GWASs using phenotype measures in UK Biobank participants (N= 487,409)” the number of participants should have been 150,509. In the sentence “Thus, a total of 110,361 European descendants with high-quality genotyping and complete phenotype/covariate data were used for these analyses, including 25,685 allergic diseases subjects (hay fever/allergic rhinitis or eczema, without doctor-diagnosed asthma), 14,085 asthma subjects and 76,768 controls for the analysis” the phrase “without doctor-diagnosed asthma” should have read “some with doctor-diagnosed asthma.” The errors have been corrected in the HTML and PDF versions of the article.