When mothering goes awry: Challenges and opportunities for utilizing evidence across rodent, nonhuman primate and human studies to better define the biological consequences of negative early caregiving.
When mothering goes awry: Challenges and opportunities for utilizing evidence across rodent, nonhuman primate and human studies to better define the biological consequences of negative early caregiving.
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DOI：
10.1016/j.yhbeh.2015.10.007
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发表时间：
2016-01
影响因子：
3.5
通讯作者：
Gonzalez A
中科院分区：
文献类型：
--
作者：
Drury SS;Sánchez MM;Gonzalez A
在哺乳动物中，母亲塑造社会情感发展，并作为婴儿生理学，大脑发育，行为模式和情感调节的重要外部调节器。护理质量、一致性和可预测性塑造了婴儿潜在的神经生物学过程。虽然对“最佳”养育的要求因物种而异，但缺乏所需养育（例如忽视）或存在有害/厌恶养育（例如身体虐待）的负面长期后果在物种之间是可以翻译的。认识到跨物种比较在确定潜在机制方面的巨大潜力，有效的翻译需要考虑物种之间的进化，生态和基本生物学和发育差异。这篇评论提供了一个概述的几个成功的跨物种翻译的故事，在有关的负面虐待和模板，为未来的研究寻求最有效地定义潜在的生物过程和推进研究，致力于减轻持久的负面健康后果的虐待儿童。
Across mammalian species, mothers shape socio-emotional development and serve as essential external regulators of infant physiology, brain development, behavior patterns, and emotional regulation. Caregiving quality, consistency and predictability shape the infant's underlying neurobiological processes. Although the requirements for “optimal” caregiving differ across species, the negative long-term consequences of the absence of needed caregiving (e.g. neglect) or the presence of harmful/aversive caregiving (e.g. physical abuse), are translatable across species. Recognizing the significant potential of cross species comparisons in terms of defining underlying mechanisms, effective translation requires consideration of the evolutionary, ecological, and fundamental biological and developmental differences between and among species. This review provides both an overview of several success stories of cross-species translations in relation to negative caregiving and a template for future studies seeking to most effectively define the underlying biological processes and advance research dedicated to mitigating the lasting negative health consequences of child maltreatment.