Ethnic differences in adiponectin levels
Ethnic differences in adiponectin levels
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DOI：
10.1016/j.metabol.2003.07.002
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发表时间：
2004-01-01
影响因子：
9.8
通讯作者：
Barakat, HA
中科院分区：
文献类型：
--
作者：
Hulver, MW;Saleh, O;Barakat, HA
研究人员测量了不同体重指数 (BMI) 的非裔美国人和白人女性的脂联素水平。比较血浆脂联素水平并评估脂联素和胰岛素敏感性之间的关系。白种人肥胖 (7.0 +/- 0.8 杯/毫升)、非裔美国人肥胖 (7.3 +/- 3.5 杯/毫升) 和非裔美国非肥胖女性 (7.1 +/- 1.2 杯/毫升) 中脂联素水平相似，但白种人非肥胖女性 (12.2 +/- 1.4 杯/毫升) 中脂联素水平显着较高。相关分析表明，只有白人女性的 BMI、胰岛素和稳态模型评估 (HOMA) 与脂联素水平显着相关。这些结果支持了以下观点：适用于其他种族人群的方法可能不适用于非裔美国人，并且需要在非裔美国人中阐明脂联素和胰岛素敏感性之间的关联。 (C) 2004 Elsevier Inc. 保留所有权利
Adiponectin levels were measured in African American and Caucasian women of varying body mass index (BMI). Plasma adiponectin levels were compared and the relationship between adiponectin and insulin sensitivity was assessed. Adiponectin levels were similar in the Caucasian obese (7.0 +/- 0.8 mug/mL), African American obese (7.3 +/- 3.5 mug/mL), and African American non-obese women (7.1 +/- 1.2 mug/mL), but were significantly higher in Caucasian non-obese women (12.2 +/- 1.4 mug/mL). Correlational analyses demonstrated that BMI, insulin, and homeostasis model assessment (HOMA) correlated significantly with adiponectin levels in only the Caucasian women. These results provide support for the notion that what applies to other ethnic populations might not apply to the African American population, and that the association between adiponectin and insulin sensitivity needs to be clarified in the African American population. (C) 2004 Elsevier Inc. All rights reserved