The Effects of Intracellular Iontophoretic Injection of Calcium and Sodium Ions on the Light Response of Limulus Ventral Photoreceptors
The Effects of Intracellular Iontophoretic Injection of Calcium and Sodium Ions on the Light Response of Limulus Ventral Photoreceptors
复制标题
细胞内离子电渗注射钙、钠离子对鲎腹侧光感受器光响应的影响
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
Joel E. Brown
中科院分区：
文献类型：
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作者：
J. Lisman;Joel E. Brown
在细胞内电泳法将Ca~(++)注入示踪的光感受器细胞过程中，光反应逐渐减弱。注射钙离子后，光反应的大小缓慢恢复。类似地，在细胞内注射Na+的过程中，光反应逐渐减弱，停止注射后恢复。Na+注射过程中，[Ca++]浓度越高，下降的速度越大。在含有0.1 mM Ca++的溶液中，在注入Na+期间，光响应的大小几乎没有逐渐减小。细胞内注射Li+或K+并不会逐渐减小光反应的大小。我们认为，[Na+]in的增加会导致[Ca++]in的增加，而[Ca++]in的增加无论如何都会导致对光的反应性降低。
During intracellular iontophoretic injection of Ca++ into Limulus ventral photoreceptor cells, there is a progressive diminution of the light response. Following Ca++ injection, the size of the light response slowly recovers. Similarly, there is a progressive diminution of the light response during intracellular injection of Na+ and recovery after the injection is stopped. The rate of diminution during Na+ injection is greater for higher [Ca++]out. In solutions which contain 0.1 mM Ca++, there is nearly no progressive decrease in the size of the light response during Na+ injection. Intracellular injections of Li+ or K+ do not progressively decrease the size of the light response. We propose that an increase in [Na+]in leads to an increase in [Ca++]in and that an increase in [Ca++]in by any means leads to a reduction in responsiveness to light.