MELATONIN - MULTIFACETED MESSENGER TO THE MASSES
MELATONIN - MULTIFACETED MESSENGER TO THE MASSES
复制标题
DOI：
10.1093/labmed/25.7.438
复制
发表时间：
1994-07-01
影响因子：
1.3
通讯作者：
REITER, RJ
中科院分区：
文献类型：
--
作者：
REITER, RJ
这是关于时间生物学的五部分继续教育系列的第三篇文章。其他文章集中于时间生物学与内分泌系统、心肌梗死和癌症医学中的时间药理学的关系。这篇文章主要关注褪黑激素，它是大脑中一小部分松果体的荷尔蒙产物。读者将学习弓褪黑激素将重要的一天中的时间和季节信息传递给所有细胞。这种吲哚胺是一种高度保守的分子，可能存在于从藻类到人类的各种有机体中。褪黑激素从松果体产生并释放到血液中，特别是在晚上，被称为黑暗的化学体验。褪黑素很容易进入生物体中的每一种液体和细胞。它还在控制内分泌和生殖生理方面发挥作用，并已被证明是一种强有力的自由基清除剂。
This is the third article in a five-part continuing education series on chronobiology. Other articles focus on chronobiology's relation to the endocrine system, myocardial infarction, and chronopharmacology in cancer medicine. This article focuses on melatonin, the hormonal product of a small part of the brain called the pineal gland. The reader will learn bow melatonin passes important time-of-day and seasonal information to all cells. This indoleamine is a highly conserved molecule that may exist in organisms ranging from algae to humans. Melatonin is produced and released from the pineal gland into the blood especially at night and is referred to as the chemical experience of darkness. Melatonin readily gains access to every fluid and cell in the organism. It also functions in the control of endocrine and reproductive physiology, and has been shown to be a potent free-radical scavenger.