Brachioradial pruritus: A symptom of neuropathy

Brachioradial pruritus: A symptom of neuropathy
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DOI:
10.1067/mjd.2003.494
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发表时间:
2003-06-01
影响因子:
13.8
通讯作者:
Vardy, DA
Vardy, DA
中科院分区:
医学1区
文献类型:
--
作者:
Cohen, AD;Masalha, R;Vardy, DA

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背景:臂放射状瘙痒(BRP)是一种局限性的臂背外侧瘙痒。BRP是一种原因有争议的神秘疾病;一些作者认为BRP是一种光皮病,而另一些作者则将BRP归因于颈神经根受压。方法:对BRP患者的正中、尺、桡神经进行电生理检查,包括正中、尺神经的感觉和运动远端潜伏期、正中、尺神经的传导速度和F反应,以及双上肢的桡神经的感觉远端潜伏期。结果:研究对象为7例患者,男5例,女2例,年龄42~72岁,平均58.3岁。其中4例(57%)F反应异常,诊断为神经根性颈椎病,其中3例神经末端潜伏期延长,可能为慢性神经根性神经病继发的感觉运动神经病。4例患者继发于糖尿病的多发性神经病变。结论:BRP可能是一种神经病变,如慢性神经根病变。在对所有BRP患者进行评估和治疗时,应考虑潜在神经病变的可能性。
Background: Brachioradial pruritus (BRP) is a localized pruritus of the dorsolateral aspect of the arm. BRP is an enigmatic condition with a controversial cause; some authors consider BRP to he a photodermatosis whereas other authors attribute BRP to compression of cervical nerve roots.Objective. We sought to investigate the presence of neuropathy in patients with BRRMethods: We performed electrophysiologic studies of the median, ulnar, and radial nerves in consecutive patients with BRP, including measurement of sensory and motor distal latency, conduction velocity and F responses of the median and ulnar nerves, and sensory distal latency of the radial nerves in both upper limbs.Results: Included in the study were 7 patients, 5 men and 2 women, with an average age of 58.3 years (range: 42-72 years). Of the patients, 4 (57%) had abnormal F responses that were diagnostic for cervical radiculopathy, and 3 of these patients had prolonged distal latencies of the nerves tested, which may be interpreted as sensory motor neuropathy secondary to chronic radiculopathy. The fourth patient had polyneuropathy secondary to diabetes mellitus.Conclusion: BRP may be attributed to a neuropathy, such as chronic cervical radiculopathy. The possibility of an underlying neuropathy should be considered in the evaluation and treatment of all patients with BRP.