Heterogeneity of multiple-pore membranes investigated with ion conductance microscopy.
Heterogeneity of multiple-pore membranes investigated with ion conductance microscopy.
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用离子电导显微镜研究多孔膜的异质性。
DOI：
10.1021/ac300257q
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发表时间：
2012
影响因子：
7.4
通讯作者：
Baker,LaneA
中科院分区：
文献类型：
--
作者：
Zhou,Yi;Chen,Chiao-Chen;Baker,LaneA
用四电极扫描离子电导显微镜（SICM）研究了多孔膜上单个孔的非均匀电导。跨膜施加电势差导致离子通过纳米孔的迁移，其中随后的电导变化通过位于纳米孔上方的纳米移液管测量为移液管电流的变化。检查了单孔膜和多孔膜内的单个孔的电流响应，并证明了由于孔几何形状的微小差异而导致的离子电流整流（ICR）比的变化。
Heterogeneous conductance of individual pores on a porous membrane was studied with a four-electrode scanning ion conductance microscope (SICM). Application of a potential difference across the membrane resulted in migration of ions through nanopores, where subsequent conductance changes were measured by a nanopipet positioned above the nanopore as a change in pipet current. Current responses of single-pore membranes and individual pores within a multipore membrane were examined and demonstrated variations in ion current rectification (ICR) ratios due to the small differences in pore geometries.