Vinylcyclopropane Derivatives in Transition-Metal-Catalyzed Cycloadditions for the Synthesis of Carbocyclic Compounds
Vinylcyclopropane Derivatives in Transition-Metal-Catalyzed Cycloadditions for the Synthesis of Carbocyclic Compounds
复制标题
用于合成碳环化合物的过渡金属催化环加成中的乙烯基环丙烷衍生物
DOI：
10.1021/jo400609w
复制
发表时间：
2013-07-19
影响因子：
3.6
通讯作者：
Yu, Zhi-Xiang
中科院分区：
文献类型：
--
作者：
Jiao, Lei;Yu, Zhi-Xiang
乙烯基环丙烷（VCP）衍生物参与多种过渡金属催化的多组分环加成反应，生成五至八元碳环。各种环加成模式为单环、双环和多环分子提供了新的方法。本文综述了近年来过渡金属催化的VCP环加成反应的研究进展，重点讨论了VCP取代方式对环加成反应模式的影响。并以表格形式总结了VCP环加成反应在天然产物合成中的应用。
Vinylcyclopropane (VCP) derivatives participate in a variety of transition-metal-catalyzed multicomponent cycloadditions to produce five- to eight-membered carbocycles. Various cycloaddition modes provide novel approaches to mono-, bi-, and polycyclic molecules. In this Synopsis, recent advances in transition-metal-catalyzed VCP cycloadditions are discussed, with a particular emphasis on the influence of VCP substitution pattern on cycloaddition modes. A tabular summary of applications of the VCP cycloadditions in natural product synthesis is also presented.