Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET
Comprehensive nutrient consumption estimation and metabolic profiling during ketogenic diet and relationship with myocardial glucose uptake on FDG-PET
复制标题
DOI：
10.1093/ehjci/jeac031
复制
发表时间：
2022-04-02
影响因子：
6.2
通讯作者：
Bravo, Paco E.
中科院分区：
文献类型：
--
作者：
Selvaraj, Senthil;Seidelmann, Sara B.;Bravo, Paco E.
生酮饮食（KD）是使用氟-18氟脱氧葡萄糖-正电子发射断层扫描（FDG-PET）评估炎症的标准治疗，以实现心肌葡萄糖抑制（MGS）。由于KD方案在不同中心之间仍然存在很大差异（包括通过膳食日志估计营养素摄入量以确保膳食准备充分），我们旨在评估营养素摄入量在实现MGS中的预测效用。方法和结果19名健康受试者接受短期KD，在KD后1天和3天（目标碳水化合物摄入量）进行FDG-PET检查
Aims The ketogenic diet (KD) is standard-of-care to achieve myocardial glucose suppression (MGS) for assessing inflammation using fluorine-18 fluorodeoxyglucose-positron emission tomography (FDG-PET). As KD protocols remain highly variable between centres (including estimation of nutrient intake by dietary logs for adequacy of dietary preparation), we aimed to assess the predictive utility of nutrient intake in achieving MGS. Methods and results Nineteen healthy participants underwent short-term KD, with FDG-PET performed after 1 and 3 days of KD (goal carbohydrate intake