Changes in lesion size after submacular surgery for subfoveal choroidal neovascularization in the submacular surgery trials pilot study.
Changes in lesion size after submacular surgery for subfoveal choroidal neovascularization in the submacular surgery trials pilot study.
复制标题
黄斑下手术试验试点研究中黄斑下中心凹下脉络膜新生血管术后病变大小的变化。
DOI：
10.1097/00006982-200412000-00008
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
SubmacularSurgeryTrialsPilotStudyInvestigators
中科院分区：
文献类型：
--
作者：
Sadda,SrinivasR;Pieramici,DanteJ;Marsh,MartaJ;Bressler,NeilM;Bressler,SusanB;SubmacularSurgeryTrialsPilotStudyInvestigators
Purpose:To compare the size of subfoveal lesions based on photographic documentation before and after submacular surgery of choroidal neovascularization (CNV) lesions.Methods:Subfoveal lesion sizes at baseline and month 3 follow-up visits for patients assigned to surgery in the Submacular Surgery Trials (SST) Pilot Study were assessed categorically using Macular Photocoagulation Study (MPS) disc area (DA) circles. The Submacular Surgery Trials Pilot Study groups reviewed were as follows: Group N (age-related macular degeneration [AMD]; lesion< 50% blood; classic CNV present; size≤ 9 MPS DAs); Group R (AMD; prior nonfoveal laser; classic CNV present; size≤ 9 MPS DAs); Group B (AMD; lesion≥ 50% blood); and Group H (ocular histoplasmosis syndrome or idiopathic; classic CNV present; size≤ 9 MPS DAs).Results:Postoperative month 3 lesion size was at least 1 size category smaller than the preoperative lesion size in 6%(4/66) of Group N, 0 (0/31) of Group R, 6%(2/34) of Group H, and 45%(18/40) of Group B eyes. In Group H eyes, there was no size change in 50%(17/34), and enlargement was found in 44%(15/34). For eyes in Groups N and R, approximately one third remained stable (20/66, 30% and 12/31, 39%, respectively), whereas two thirds enlarged by at least 1 category (42/66, 64% and 19/31, 61%, respectively).Conclusions:The change in lesion size after submacular surgery was variable, with a tendency for Group H lesions to remain the same size or larger, Group B lesions to measure smaller, and Group N and Group R lesions to be larger.
