Ontogeny of bladder compliance
Ontogeny of bladder compliance
复制标题
膀胱顺应性的个体发育
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
R. Levin
中科院分区：
文献类型：
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作者：
S. Zderic;J. Duckett;H. Snyder;A. Wein;R. Levin
最近的技术进步允许通过使用产前超声诊断许多泌尿系统异常。在儿科文献中，关于通过产前超声诊断的肾积水是否总是继发于梗阻，或者在某些情况下代表良性扩张，存在很大的争议。良性膀胱炎被认为是继发于胎儿多尿和胎儿泌尿道顺应性增加。在这项研究中，我们提出了膀胱顺应性随着成熟而逐渐下降的证据。我们的结果的总结表明，从1日龄兔子获得的膀胱比4-8周龄兔子的膀胱更顺应性2和3倍。当肌肉被拉伸到其初始静止长度的150%时，主动张力达到峰值。然而，与从4和8周龄兔获得的膀胱组织的反应相比，1天大的膀胱组织表现出对场刺激的反应更高的主动张力。总之，顺应性和主动张力随着成熟而降低。
Recent advances in technology have allowed for the diagnosis of many urologic abnormalities through the use of antenatal ultrasonography. There is great debate in the pediatric literature as to whether the hydronephrosis which is diagnosed via antenatal ultrasound is always secondary to obstruction, or in certain cases represents a benign dilatation. Benign dilatations are postulated to be secondary to the increased fetal diuresis and a more compliant fetal urinary tract. In this study we present evidence for a gradual decline in bladder compliance with maturation. A summary of our results demonstrates that bladders obtained from 1 day old rabbits are 2 and 3 times more compliant than bladders of 4–8 week old rabbits. Active tension reaches a peak when the muscle is stretched to 150% of its initial resting length. However, 1 day old bladder tissue exhibits a higher active tension in response to field stimulation when compared to the response of bladder tissue obtained from 4 and 8 week old rabbits. In summary, compliance and active tension decrease with maturation.
兔子膀胱功能的个体发育。
DOI：
10.1016/s0022-5347(17)39588-5
发表时间：
1990
期刊：
The Journal of urology
影响因子：
--
作者：
Keating,MA;Duckett,JW;Snyder,HM;Wein,AJ;Potter,L;Levin,RM
通讯作者：
Levin,RM